Invasive Salmonellosis in Malawi
J. infect. dev. ctries
;
2(6): 438-443, 2008.
Article
in English
| AIM
| ID: biblio-1263574
ABSTRACT
The incidence of invasive salmonellosis has increased among children and HIV-infected adults in Malawi. This has been associated with the emergence of drug resistance in the non-typhoidal Salmonella serovars Enteritidis and Typhimurium. In contrast; S. Typhi isolates have remained fully sensitive to commonly used antibiotics and the estimated incidence of typhoid fever; although still present; has fallen slightly among both adults and children. Infection with S. Typhi is not closely associated with underlying immuno- suppression but it is possible that the non-typhoidal Salmonellae have adapted to the person-person human transmission niche in this frequently immunosuppressed population. The huge burden of invasive salmonellosis in Malawi; the high associated mortality; and the recent emergence of drug resistance emphasise the need for a better understanding of the epidemiology and the need for vaccine development
Full text:
Available
Index:
AIM (Africa)
Main subject:
Salmonella Infections
/
HIV Infections
/
Child
/
Immunosuppression Therapy
/
Adult
Language:
English
Journal:
J. infect. dev. ctries
Year:
2008
Type:
Article
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