Increase in the Detection Rate of Viral and Parasitic Enteric Pathogens among Egyptian Children with Acute Diarrhea
J. infect. dev. ctries
;
6(11): 774-781, 2012.
Article
in English
| AIM
| ID: biblio-1263618
ABSTRACT
Introduction:
Acute diarrhea continues to be a major cause of morbidity and mortality in children from developing countries. Determination of the frequency of diarrhea in an area; along with the proportion of disease caused by specific enteric agents of different origins; is considered the first step in controlling diarrheal diseases.Methodology:
From 2005 to 2007; a hospital-based surveillance was conducted in two locations in Egypt to determine the causes of acute diarrhea in children younger than 5-years seeking treatment. Five additional enteric viral and parasitic pathogens were tested using commercially-available enzyme immunoassays (EIA) to re-evaluate the prevalence of diarrheal pathogens in undiagnosed cases.Results:
Adenovirus; astrovirus; norovirus and G. lamblia were detected as the sole pathogen in 2 (n=34); 3 (n=56); 9 (n=191) and 7 (n=146) of the cases; respectively. E. histolytica was never detected as the sole pathogen. The percentage of diarrheal cases with a known cause increased significantly; from 48 (n=1;006) to 74 (n=1;568) (P0.0001).Conclusion:
In our study; the incorporation of immunoassays yielded useful data in identifying pathogens in previously pathogen-negative diarrhea cases
Full text:
Available
Index:
AIM (Africa)
Main subject:
Attitude to Health
/
Diarrhea
Type of study:
Diagnostic study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
J. infect. dev. ctries
Year:
2012
Type:
Article
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