Ophthalmic disorders in Adult Lymphoma Patients in Africa
Middle East Afr. j ophthalmol. (Online)
;
16(4): 252-255, 2009.
Article
in English
| AIM
| ID: biblio-1266523
ABSTRACT
Context Ocular manifestations of lymphoma are rare events. Most reports of ocular involvement in lymphoma are case reports or reports of a few patients. Aims:
To determine the ophthalmic disorders in adult; African; lymphoma patients. Settings andDesign:
A prospective study of ocular disorders in adult patients with lymphoma was conducted at the University of Benin Teaching Hospital; Benin City; Nigeria; between July 2004 and June 2007. Materials andMethods:
The patients were interviewed and examined by the authors and the ocular findings recorded. StatisticalAnalysis:
Data was analyzed on computer with the aid of the Instat GraghPadT v2.05a statistical package software. The mean; standard deviation; Mann-Whitney U-statistic and P value were calculated.Results:
A total of 111 patients with hematological malignancies were seen over a period of three years of which 62 (55.85) had lymphomas. Of these; 51(82.3) were non-Hodgkin's lymphoma and 11(17.7) were Hodgkin's lymphoma. Ocular disorders occurred in 16 patients (31.4) with non-Hodgkin's lymphoma and none of the patients with Hodgkin's lymphoma (Mann-Whitney U-statistic is equal to 7.500; U' is equal to161.50; P ; 0.0001). The ocular disorders due to non-Hodgkin's lymphoma were seen as - proptosis in six patients (11.8); retinopathies in three (5.9); conjunctival infiltration in three (5.9); optic atrophy in two (3.9); keratoconjunctivitis in one (two per cent); desquamating nodular lid lesions in one (two per cent); papilloedema in one (two per cent); and upper lid mass in one (two per cent). Four patients (6.5) had monocular blindness.Conclusions:
Ophthalmic disorders are relatively common in non-Hodgkin's lymphoma. Ophthalmic evaluation is needed in these patients for early identification and treatment of potentially blinding conditions
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Index:
AIM (Africa)
Main subject:
Adult
/
Eye Manifestations
/
Lymphoma
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Middle East Afr. j ophthalmol. (Online)
Year:
2009
Type:
Article
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