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Statistical study of the relationship between hyperuricemia, dyslipidemia and type 2 diabetes in rural population of Tizi-Ouzou, Algeria
Lefsih, Khalef; Dahmani, Dalila; Cherrad, Rabah; Lalaoui, Souad; Amrar, Sarah.
  • Lefsih, Khalef; s.af
  • Dahmani, Dalila; s.af
  • Cherrad, Rabah; s.af
  • Lalaoui, Souad; s.af
  • Amrar, Sarah; s.af
NAJFNR ; 4(7): 268-279, 2020.
Article in English | AIM | ID: biblio-1266919
ABSTRACT

Aim:

The main objective of our work was to assess the relationship between type 2 diabetes, hyperuricemia and dyslipidemia in the population of Tizi-Ouzou. By evaluating the relationship between hyperuricemia and some blood lipid parameters, we thus establish, in type 2 diabetes, the correlation between uremia and these lipid parameters. Subjects and

methods:

The survey was carried out by means of an individual questionnaire. We excluded from our study pregnant women, patients with cancer, patients with end-stage renal disease and subjects who did not respond to the questionnaire.

Results:

Serum uric acid level increased with age (p = 0.025). Hyperuricemia was associated with heart disease (p = 0.0007). All patients with gout presented an elevated serum uric acid (p = 0.000001). Dyslipidemia was more common in patients with elevated serum uric acid levels (p = 0.0008). Triglyceridemia was significantly associated with hyperuricemia (p = 0.025). The relationship between type 2 diabetes and glomerular filtration rate was not significant, while the latter was decreased in patients with elevated serum uric acid levels (p = 0.0001). In, stratified analysis, age was effect modifier, the age-dependent results make us understand that resistance to insulin constitutes a significant factor of hyperuricemia.

Conclusion:

The association between hyperuricemia and dyslipidemia in type 2 diabetes emphasizes that insulin resistance acts on both lipid parameters and uricemia. A diet correcting dyslipidemia may also correct the uricemia
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Index: AIM (Africa) Main subject: Hyperuricemia / Algeria / Dyslipidemias / Lipoproteins Country/Region as subject: Africa Language: English Journal: NAJFNR Year: 2020 Type: Article

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Index: AIM (Africa) Main subject: Hyperuricemia / Algeria / Dyslipidemias / Lipoproteins Country/Region as subject: Africa Language: English Journal: NAJFNR Year: 2020 Type: Article