Changing Concepts in the Management of Peptic Ulcer

ABSTRACT

Over the years; the treatment of duodenal ulcer disease seems to be based on beliefs and scattered facts with weak scientific basis. There is little evidence that the use of antacids; anti-secretory drugs; diet regulation; sedatives and pepsin inhibitors; even though they reduce the ulcer pain; prevent recurrence of ulcer and healing of ulcer in all cases. Recently; the finding of Helicobacter pylori in association with peptic ulcer disease seems to confirm that this is probably a most important aetiological factor for peptic ulcer disease. Presently; treatment of peptic ulcer is directed at eradicating this bacterium. This review paper highlights the evolution of the surgical procedures for peptic ulcer disease