Cytomegalovirus (CMV)
S. Afr. gastroenterol. rev
;
16(3): 23-26, 2018.
Article
in English
| AIM
| ID: biblio-1270161
ABSTRACT
Cytomegalovirus (CMV) is a member of the Herpes virus group. It is a double stranded DNA virus and is known as Human Herpes Virus 5 in human hosts. CMV seropositivity is frequent in Western populations with a seroprevalence of 58% being reported in the U.S.1 In Africa, pooled prevalence studies demonstrate rates as high as 81.8% amongst HIV uninfected adults. Amongst the HIV infected population prevalence rates of 81.9% and 94.8% were seen in AIDS and asymptomatic HIV positive patients respectively.2 This is likely a reflection of impaired humoral immunity amongst those with AIDS. In a rural South African cohort, a 100% seroprevalence was demonstrated amongst HIV positive treatment naïve patients with a negative association noted between CD4 counts and IgG titres.3
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Index:
AIM (Africa)
Main subject:
South Africa
/
Cytomegalovirus Vaccines
Type of study:
Risk factors
Country/Region as subject:
Africa
Language:
English
Journal:
S. Afr. gastroenterol. rev
Year:
2018
Type:
Article
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