An overview of cancer research in South African academic and research institutions, 2013 - 2014

ABSTRACT

BACKGROUND AND OBJECTIVES:Cancer is emerging as a critical public health problem in South Africa (SA). Recognising the importance of research in addressing the cancer burden; the Ministerial Advisory Committee on the Prevention and Control of Cancer (MACC) research working group undertook a review of the current cancer research landscape in SA and related this to the cancer burden.METHODS:Academic and research institutions in SA were contacted to provide information on the titles of all current and recently completed (2013/2014) cancer research projects. Three MACC research working group members used the project titles to independently classify the projects by type of research (basic; clinical and public health - projects could be classified in more than one category) and disease site. A more detailed classification of projects addressing the five most common cancers diagnosed in males and females in SA was conducted using an adapted Common Scientific Outline (CSO) categorisation.RESULTS:Information was available on 556 cancer research projects. Overall; 301 projects were classified as clinical; 254 as basic science and 71 as public health research. The most common cancers being researched were cancers of the breast (n=95 projects) and cervix (n=43); leukaemia (n=36); non-Hodgkin's lymphoma (n=35) and lung cancer (n=23). Classification of the five most common cancers in males and females in SA; using the adapted CSO categories; showed that the majority of projects related to treatment; with relatively few projects on prevention; survivorship and patient perspectives.CONCLUSION:Our findings established that there is a dearth of public health cancer research in SA