Effects of Medication with Ivermectin; Chloroquine and Artemether on Plasma Nitrate / nitrite Levels in Calves Naturally Infected with Onchocerca Gutturosa

ABSTRACT

In a comparative study involving the use of Ivermectin; Chloroquine and Artemether against Onchocerca gutturosa in calves; the plasma nitrate /nitrite concentration was measured. Following treatment and clearance of skin mf of O. gutturosa; the plasma nitrate/ nitrite concentrations; nor the stable end product of Nitric Oxide (NO) breakdown; rise significantly although it showed short peaks following reduction in dermal mf counts but no clear correlation was detected