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Ultrasonographic enthesis evaluation in patients with recurrent acute anterior uveitis with and without spondyloarthropathy
Nooreldin, Asaad; Abdelkareem, Mohamed Ismail; Ibrahim, Ahmed Moslam; Mahmou, Amr Mohamed.
  • Nooreldin, Asaad; s.af
  • Abdelkareem, Mohamed Ismail; s.af
  • Ibrahim, Ahmed Moslam; s.af
  • Mahmou, Amr Mohamed; s.af
The Egyptian Journal of Hospital Medicine ; 76(7): 4608-4615, 2019. ilus
Article in English | AIM | ID: biblio-1272781
ABSTRACT

Background:

spondyloarthritis (SpA) is a group of chronic diseases recognized by arthritis and extraarticular lesions e.g. uveitis, enthesitis, dermatological affection. About 35% of SpA patients may present with recurrent attacks of acute anterior uveitis (AAU).

Purpose:

it was to detect whether patients with idiopathic recurrent AAU who were positive or negative for Human Leukocyte Antigen B27 (HLA­B27) had a frequency of enthesis lesions compared to that seen in patients with SpA. Patients and

Methods:

a prospective study of enthesis evident on musculoskeletal ultrasound examination was done on sixty patients and twenty controls, the eighty were categorized into 4 groups; group 1 included 20 patients with known SpA group 2 included 20 with recurrent AAU HLA­B27 positive and didn't have SpA aspects group 3 included 20 with recurrent AAU HLA­B27 negative and didn't have SpA and group 4 included 20 healthy controls. Using Madrid Sonography Enthesitis Index (MASEI) twelve enthesis locations were assessed in each participant.

Results:

a total of 960 entheses sites were examined by ultrasonography in all 80 participants. The MASEI cut-off limit of ≥18 points was 75%, 60%, 45%, and 10% of the participants in the 4 groups; respectively. The MASEI score was significantly higher in groups 1&2 than in groups 3&4. The differences between the two groups were statistically significant.

Conclusion:

a high percent of HLA­B27 positive patients with idiopathic recurrent AAU without characteristics of SpA have enthesis lesions with about percent to those seen in patients with known SpA
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Index: AIM (Africa) Main subject: Uveitis / Ultrasonography / Spondylarthritis Type of study: Diagnostic study / Observational study Language: English Journal: The Egyptian Journal of Hospital Medicine Year: 2019 Type: Article

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Index: AIM (Africa) Main subject: Uveitis / Ultrasonography / Spondylarthritis Type of study: Diagnostic study / Observational study Language: English Journal: The Egyptian Journal of Hospital Medicine Year: 2019 Type: Article