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Impacto del uso de PCR múltiple en diagnóstico etiológico y tratamiento de infecciones respiratorias agudas en un hospital privado del norte del país / Impact of the use of multiplex PCR on etiological diagnosis and treatment of acute respiratory infections in a private hospital of the north of the country
Hernández-González, Diana G; Rodríguez-Muñoz, Lorena; Solórzano-Santos, Fortino.
  • Hernández-González, Diana G; Hospital Christus Muguer. Departamento de pregrado. Saltillo. MX
  • Rodríguez-Muñoz, Lorena; Hospital Christus Muguerza. Departamento de Infectología pediátrica. Saltillo. MX
  • Solórzano-Santos, Fortino; Instituto Nacional de Salud. Hospital Infantil de México Federico Gómez. Unidad de Investigación en Enfermedades Infecciosas. Ciudad de México. MX
Gac. méd. Méx ; 157(2): 160-165, mar.-abr. 2021. graf
Article in Spanish | LILACS | ID: biblio-1279096
RESUMEN
Resumen Antecedentes y

objetivo:

Las enfermedades del sistema respiratorio son causa frecuente de prescripción de antibióticos. Actualmente se emplean nuevas tecnologías para su diagnóstico como el FilmArray Respiratory Panel. El objetivo de este estudio es identificar la correlación entre el diagnóstico y tratamiento de infecciones de vías respiratorias con el resultado de PCR para virus respiratorios. Material y

métodos:

Estudio descriptivo, transversal, retrospectivo, se incluyeron 134 pacientes atendidos en el Hospital Christus Muguerza en Saltillo, Coahuila. Para todos los casos se analizaron los resultados del panel y el tratamiento que recibieron los pacientes.

Resultados:

El 58 % recibió tratamiento antibiótico a su ingreso, el 13 % tratamiento combinado (antibiótico + antiviral), 27 % recibió tratamiento sintomático y el 2 % fue tratado con antiviral de primera instancia. Posterior al resultado el 38 % continuó con antibiótico, el 30 % con antibiótico y antiviral, 13.8 % se manejó con antiviral y el 18.2 % con tratamiento sintomático.

Conclusión:

A pesar de la alerta mundial por la resistencia a los antimicrobianos se sigue tratando a los pacientes con antibióticos, por una situación que se cree está influenciada por varios factores.
ABSTRACT
Abstract Background and

objective:

Respiratory system diseases represent one of the leading cause of prescription of antibiotics. At present, new technologies for the diagnosis are being used, including the FilmArray Respiratory Panel. The objective was to identify the correlation between the diagnosis and treatment of respiratory tract infections with the result of PCR for respiratory viruses. Material and

methods:

Descriptive, cross-sectional, restrospective study. 134 patients were included treated at the Christus Muguerza Hospital in Saltillo, Coahuila. For all cases, the positive results of this test and the treatment patients received were analyzed.

Results:

58 % received antibiotic treatment at admission, 13 % received combined treatment (antibiotic + antiviral), 27 % received symptomatic treatment since their admission and 2 % whit antiviral. After receiving a positive result for respiratory viruses, 38 % continued with antibiotics, 30 % with antibiotics and antivirals, 13.8 % only managed with antivirals and 18.2% with symptomatic treatment.

Conclusion:

Although we are currently on global alert for resistance to antibiotics, there is a lack of awareness about the prescription of antibiotics, due to a situation which is believed to be influenced by several factors.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Respiratory Tract Infections / Virus Diseases / Multiplex Polymerase Chain Reaction / Anti-Bacterial Agents Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Mexico Language: Spanish Journal: Gac. méd. Méx Journal subject: Medicine Year: 2021 Type: Article Affiliation country: Mexico Institution/Affiliation country: Hospital Christus Muguer/MX / Hospital Christus Muguerza/MX / Instituto Nacional de Salud/MX

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Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Respiratory Tract Infections / Virus Diseases / Multiplex Polymerase Chain Reaction / Anti-Bacterial Agents Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Mexico Language: Spanish Journal: Gac. méd. Méx Journal subject: Medicine Year: 2021 Type: Article Affiliation country: Mexico Institution/Affiliation country: Hospital Christus Muguer/MX / Hospital Christus Muguerza/MX / Instituto Nacional de Salud/MX