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Systemic ALK-positive anaplastic large cell lymphoma involving implant site: a fortuitous association
Parkhi, Mayur; Singh, Charanpreet; Kumar, Rajender; Malhotra, Pankaj; Bal, Amanjit.
  • Parkhi, Mayur; Post Graduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
  • Singh, Charanpreet; Post Graduate Institute of Medical Education and Research. Department of Clinical hematology. Chandigarh. IN
  • Kumar, Rajender; Post Graduate Institute of Medical Education and Research. Department of Nuclear Medicine. Chandigarh. IN
  • Malhotra, Pankaj; Post Graduate Institute of Medical Education and Research. Department of Clinical hematology. Chandigarh. IN
  • Bal, Amanjit; Post Graduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
Autops. Case Rep ; 11: e2021296, 2021. graf
Article in English | LILACS | ID: biblio-1285389
ABSTRACT
Anaplastic lymphoma kinase (ALK) positive, anaplastic large cell lymphoma involving the non-mammary implant is an extremely rare presentation. Irrespective of the type or site, the implant-associated primary ALCL is morphologically and immunophenotypically similar to ALK-negative ALCLs. Herein, we present the case of a 42-year-old male who developed a lytic lesion after an implant for a right femur fracture. The lytic lesion biopsy revealed anaplastic large cell lymphoma with ALK protein expression. Imaging findings showed the widespread dissemination of disease all over the body, entrapping the implant too. ALCL involving the bone implant is a very unusual and rare presentation that needs to be documented.
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Full text: Available Index: LILACS (Americas) Main subject: Lymphoma, Large-Cell, Anaplastic / Femoral Fractures / Anaplastic Lymphoma Kinase Type of study: Risk factors Limits: Adult / Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: India Institution/Affiliation country: Post Graduate Institute of Medical Education and Research/IN

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Full text: Available Index: LILACS (Americas) Main subject: Lymphoma, Large-Cell, Anaplastic / Femoral Fractures / Anaplastic Lymphoma Kinase Type of study: Risk factors Limits: Adult / Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: India Institution/Affiliation country: Post Graduate Institute of Medical Education and Research/IN