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HTLV-1 infection in acute t- lymphocytic leukemia/lymphoma
Department of PathologyBarouqa, Mohammad; Department of PathologyGil, Morayma Reyes; Department of PathologySekhri, Radhika; Department of PathologyPopoola, Mojisola; Department of PathologyDing, Juan; Department of PathologyWang, Yanhua.
  • Department of PathologyBarouqa, Mohammad; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologyBarouqa, Mohammad. Bronx. US
  • Department of PathologyGil, Morayma Reyes; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologyGil, Morayma Reyes. Bronx. US
  • Department of PathologySekhri, Radhika; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologySekhri, Radhika. Bronx. US
  • Department of PathologyPopoola, Mojisola; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologyPopoola, Mojisola. Bronx. US
  • Department of PathologyDing, Juan; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologyDing, Juan. Bronx. US
  • Department of PathologyWang, Yanhua; University Hospital of Albert Einstein College of Medicine. Montefiore Medical Center. Department of PathologyWang, Yanhua. Bronx. US
Autops. Case Rep ; 11: e2021307, 2021. tab, graf
Article in English | LILACS | ID: biblio-1285426
ABSTRACT
Adult T- lymphocyte leukemia/ lymphoma (ATLL), described by Uchiyama et al. in 1977, is a distinct neoplasia of peripheral T-lymphocytes caused by human T-cell lymphotropic virus type 1 (HTLV-1). The authors describe the case of a 75-year-old female patient who presented with fever, chills, and altered mental status. The peripheral blood morphology showed large atypical lymphocytes with multilobed nuclei and flow cytometry consistent with ATLL. The authors discuss the pathophysiology, differential diagnosis, and subtypes of ATLL in addition to the diagnostic approach using flow cytometry when bone marrow biopsy is not available and modalities of treatment.
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Full text: Available Index: LILACS (Americas) Main subject: Human T-lymphotropic virus 1 / Leukemia-Lymphoma, Adult T-Cell Type of study: Diagnostic study Limits: Aged / Female / Humans Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: United States Institution/Affiliation country: University Hospital of Albert Einstein College of Medicine/US

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Full text: Available Index: LILACS (Americas) Main subject: Human T-lymphotropic virus 1 / Leukemia-Lymphoma, Adult T-Cell Type of study: Diagnostic study Limits: Aged / Female / Humans Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: United States Institution/Affiliation country: University Hospital of Albert Einstein College of Medicine/US