Performance of the equations to estimate the glomerular filtration rate in Mexican patients receiving kidney transplantation / Desempeño de las ecuaciones para estimar la tasa de filtración glomerular en pacientes mexicanos receptores de trasplante renal
Gac. méd. Méx
;
155(3): 223-228, may.-jun. 2019. tab, graf
Article
in English, Spanish
| LILACS
| ID: biblio-1286495
ABSTRACT
Abstract Introduction:
The management of kidney transplant recipients requires glomerular filtration rate (GFR) monitoring, which is an indicator of graft primary function and patient survival.Objective:
To evaluate the performance of different creatinine or cystatin-based formulas in the estimation of glomerular filtration rate in Mexican patients receiving kidney transplantation.Method:
30 transplant recipients were included, in whom the glomerular filtration rate was measured by means of iothalamate, and was also calculated using seven equations based on cystatin or creatinine.Results:
The formula with the best performance was the one proposed by the chronic kidney disease epidemiology collaboration (CKD-EPI), with a bias of −2.4 mL/min/1.73 m2 and an accuracy of 9.6; 96.7 % of patients were within 30 % of the measured GFR. The second best formula was the modification of diet in renal disease (MDRD) equation. Cystatin-based equations showed a poor performance.Conclusions:
Our study suggests that, in Mexican patients receiving kidney transplantations, the best equations to estimate GFR are the CKD-EPI and MDRD equations.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Kidney Transplantation
/
Creatinine
/
Renal Insufficiency, Chronic
/
Cystatin C
/
Glomerular Filtration Rate
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Mexico
Language:
English
/
Spanish
Journal:
Gac. méd. Méx
Journal subject:
Medicine
Year:
2019
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Hospital Central Dr. Ignacio Morones Prieto/MX
/
Instituto Mexicano del Seguro Social/MX
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