Morphea: a practical review of its diagnosis, classification and treatment
Gac. méd. Méx
;
155(5): 483-491, Sep.-Oct. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1286547
ABSTRACT
Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.
Full text:
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Index:
LILACS (Americas)
Main subject:
Scleroderma, Localized
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Gac. méd. Méx
Journal subject:
Medicine
Year:
2019
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Nacional de Pediatría/MX
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