Surgical insights for the management of variant histology in renal cell carcinoma
Int. braz. j. urol
;
47(5): 935-942, Sept.-Oct. 2021. tab
Article
in English
| LILACS
| ID: biblio-1286796
ABSTRACT
ABSTRACT Purpose:
To review the current literature regarding variant (non-clear) histology of renal cell carcinoma (RCC) and the clinical management of these renal tumors. Material andMethods:
A PubMed database search was performed in May 2020 focusing on variant RCC, its diagnosis and associated syndromes, tumor characteristics, and options for management.Results:
A broad range of pathological, clinical and diagnostic characteristics amongst non-ccRCC variants were found to have an impact on the overall management of these tumors. The imaging modalities, frequency of surveillance, and timing for intervention were found to be dependent on the type of genetic alterations, type of histology, and tumor growth rates. The timing and type of surgery as well as the systemic therapy are tailored to the specific tumor type and patient.Conclusion:
The findings of this review suggest that clinical management should be considered and adjusted for patients with non-ccRCC histological variants based on tumor subtype and genetic alterations.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Carcinoma, Renal Cell
/
Kidney Neoplasms
Type of study:
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2021
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
SUNY Upstate Medical University/US
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