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Metabolic Syndrome and Risk of Cardiovascular Diseases in Female Breast Cancer Survivors
Silva, Leandro Marque da; Figueiredo Neto, José Albuquerque de.
  • Silva, Leandro Marque da; Universidade Federal do Maranhão. São Luís. BR
  • Figueiredo Neto, José Albuquerque de; Universidade Federal do Maranhão. São Luís. BR
Int. j. cardiovasc. sci. (Impr.) ; 34(4): 420-430, July-Aug. 2021. tab, graf
Article in English | LILACS | ID: biblio-1286833
ABSTRACT
Abstract Background The implementation of intensive therapy protocols increases the probability of adverse events in patients with breast cancer (BC). Components of metabolic syndrome (MS) are among these events. Objective To verify the prevalence of MS and cardiovascular disease (CVD) risk in female BC survivors. Materials and Methods This is a descriptive, observational, cross-sectional study. Our sample comprised 60 women without BC (G1) and 60 women who had survived BC (G2). We collected sociodemographic, anthropometric, tumor, and clinical data. After variable analysis, the participants received positive or negative MS diagnoses and a 10-year CVD risk stratification. The significance level adopted for the analyses was 5% ( p < 0.05) and the confidence interval (CI) was 95%. For comparing categorical data, we used the chi-squared, Fisher's exact, or G tests; for comparing continuous data, we used the parametric Student's t-test and the non-parametric Mann-Whitney test. Results Both groups presented overweight and an increased waist-to-hip ratio. Weight, body mass index, abdominal circumference, hip circumference, and low-density cholesterol were variables that presented statistically significant differences between groups. MS was diagnosed in 32% of women in G1 and 45% of those in G2. Regarding the 10-year risk for CVD, most women were in the low-risk stratum the mean total risk of CVD occurrences was 7.48% in G1 and 7.70% in G2. Conclusion We observed a higher prevalence of MS among women who survived BC, possibly due to overweight, as well as a low 10-year risk for CVD after cancer treatment. Although we did not observe a statistically significant difference, we suggest the adoption of a healthy lifestyle and rigorous control of cardiometabolic risk factors.
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Full text: Available Index: LILACS (Americas) Main subject: Breast Neoplasms / Metabolic Syndrome / Cardiometabolic Risk Factors Type of study: Etiology study / Practice guideline / Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Maranhão/BR

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Full text: Available Index: LILACS (Americas) Main subject: Breast Neoplasms / Metabolic Syndrome / Cardiometabolic Risk Factors Type of study: Etiology study / Practice guideline / Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Maranhão/BR