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Irritable bowel syndrome in Indonesian adolescents
Kesuma, Yudianita; Sekartini, Rini; Timan, Ina S; Kurniawan, Agnes; Bardosono, Saptawati; Firmansyah, Agus; Vandenplas, Yvan.
  • Kesuma, Yudianita; Sriwijaya University and Moh Hoesin Hospital. Faculty of Medicine. Department of Pediatrics. Palembang. ID
  • Sekartini, Rini; University of Indonesia and Cipto Mangunkusumo Hospital. Faculty of Medicine. Department of Pediatrics. Jakarta. ID
  • Timan, Ina S; University of Indonesia Cipto Mangunkusumo Hospital. Faculty of Medicine. Department of Clinical Pathology. Jakarta. ID
  • Kurniawan, Agnes; University of Indonesia. Faculty of Medicine. Department of Parasitology. Jakarta. ID
  • Bardosono, Saptawati; University of Indonesia. Faculty of Medicine. Department of Nutrition. Jakarta. ID
  • Firmansyah, Agus; University of Indonesia and Cipto Mangunkusumo Hospital. Faculty of Medicine. Department of Pediatrics. Jakarta. ID
  • Vandenplas, Yvan; Free University of Brussels. UZ Brussel Hospital. KidZ Health Castle. Brussels. BE
J. pediatr. (Rio J.) ; 97(2): 197-203, Mar.-Apr. 2021. tab, graf
Article in English | LILACS | ID: biblio-1287031
ABSTRACT
Abstract

Objective:

Irritable bowel syndrome is a frequent functional gastrointestinal disorder. The aims of this study were to investigate its epidemiology, focusing on the role of intestinal mucosal integrity and to evaluate the impact on the quality of life.

Methods:

A community-based survey applying a comparative cross sectional approach was conducted in six high schools in Palembang. Subjects were recruited using multistage random sampling divided in two groups. Rome III criteria were used to establish a diagnosis of IBS in combination with a questionnaire to determine risk factors. Determination of fecal alpha-1-antitrypsin and calprotectin levels was performed to determine impaired intestinal mucosal integrity. A questionnaire was used to evaluate how quality of life was affected by irritable bowel syndrome.

Results:

The survey was performed in 454 14−18 years old adolescents, of whom 30.2% fulfilled the Rome III criteria for IBS, with the following subtypes 36.5% diarrhea, 18.9% constipation, 21.9% mixed, and 22.6% unclassified. Major risk factors were female gender, bullying, age 14-16 years, history of constipation and diarrhea, eating nuts, and drinking coffee, tea, and soft drinks. There was a significant association with intestinal inflammation (p = 0.013). A significantly impaired quality of life was found (p = 0.001).

Conclusions:

The prevalence of irritable bowel syndrome in adolescents was high, with bullying, female gender, age 14-16 years, constipation and diarrhea, and dietary consumption of soft drinks, coffee, and tea as risk factors. A significant association with intestinal inflammation was found.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Irritable Bowel Syndrome Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: J. pediatr. (Rio J.) Journal subject: Pediatrics Year: 2021 Type: Article Affiliation country: Belgium / Indonesia Institution/Affiliation country: Free University of Brussels/BE / Sriwijaya University and Moh Hoesin Hospital/ID / University of Indonesia Cipto Mangunkusumo Hospital/ID / University of Indonesia and Cipto Mangunkusumo Hospital/ID / University of Indonesia/ID

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Full text: Available Index: LILACS (Americas) Main subject: Irritable Bowel Syndrome Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: J. pediatr. (Rio J.) Journal subject: Pediatrics Year: 2021 Type: Article Affiliation country: Belgium / Indonesia Institution/Affiliation country: Free University of Brussels/BE / Sriwijaya University and Moh Hoesin Hospital/ID / University of Indonesia Cipto Mangunkusumo Hospital/ID / University of Indonesia and Cipto Mangunkusumo Hospital/ID / University of Indonesia/ID