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Creating Antibacterial Properties in Flowable Dental Composites by Incorporation of 3, 4-dihydropyrimidin-2(1H)-ones
Abaszadeh, Mehdi; Mohammadzadeh, Iman.
  • Abaszadeh, Mehdi; Kerman University of Medical Sciences. Institute of Neuropharmacology. Pharmaceutics Research Center. Kerman. IR
  • Mohammadzadeh, Iman; Kerman University of Medical Sciences. Oral and Dental Disease Research Center. Kerman. IR
Article in English | LILACS, BBO | ID: biblio-1287481
ABSTRACT
ABSTRACT

Objective:

To investigate the antibacterial, mechanical, physical properties and water sorption of flowable dental composites containing 3,4-dihydropyrimidin-2(1H)-ones. Material and

Methods:

3,4-dihydropyrimidin-2(1H)-ones was synthesized and the antibacterial activity of flowable dental composites containing 0-5 wt% 3,4-dihydropyrimidin-2(1H)-ones and also of their mechanical and physical properties on flowable dental composites were investigated. Flexural strength was measured by a three-point bending test. Compressive strength (CS), Water sorption (WS) and depth of cure (DOC) were investigated. The data were analyzed by One-way ANOVA test. The level of significance was determined as p<0.01.

Results:

The direct contact test demonstrates that by increasing the 3,4-dihydropyrimidin-2(1H)-ones content, the bacterial growth is significantly diminished (p<0.001). The average flexural strength results show that with increasing 3,4-dihydropyrimidin-2(1H)-ones until 3% in the composite, no significant difference was observed in flexural strength (p>0.001) and the mean of compressive strength results show no significant difference between 0-4% groups (p>0.001). The mean of water sorption and depth of cure results shows no significant difference between groups (p>0.001).

Conclusion:

Incorporation of 3,4-dihydropyrimidin-2(1H)-ones into flowable resin composites in 3% wt can reduce the activity of Streptococcus mutans.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Streptococcus mutans / Microbial Sensitivity Tests / Composite Resins / Compressive Strength / Anti-Bacterial Agents Country/Region as subject: Asia Language: English Journal: Pesqui. bras. odontopediatria clín. integr Journal subject: Dentistry Year: 2021 Type: Article Affiliation country: Iran Institution/Affiliation country: Kerman University of Medical Sciences/IR

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Full text: Available Index: LILACS (Americas) Main subject: Streptococcus mutans / Microbial Sensitivity Tests / Composite Resins / Compressive Strength / Anti-Bacterial Agents Country/Region as subject: Asia Language: English Journal: Pesqui. bras. odontopediatria clín. integr Journal subject: Dentistry Year: 2021 Type: Article Affiliation country: Iran Institution/Affiliation country: Kerman University of Medical Sciences/IR