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Postoperative transient elevation of serum cancer antigen 125 in non-small cell lung cancer patients
Ye, Yiwang.
  • Ye, Yiwang; Peking University Shenzhen Hospital. Shenzhen. CN
Rev. Assoc. Med. Bras. (1992) ; 67(1): 39-44, Jan. 2021. tab, graf
Article in English | LILACS | ID: biblio-1287789
ABSTRACT
SUMMARY

OBJECTIVE:

The aim of this retrospective study was to investigate the correlation of transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer.

METHODS:

A total of 181 non-small cell lung cancer patients with normal levels of preoperative serum cancer antigen 125 were statistically summarized in this study.

RESULTS:

Out of the analyzed patients, 22 (12.2%) showed elevation of serum cancer antigen 125 within one month after surgery. Serum cancer antigen 125 level decreased to normal at three months postoperation. Serum cancer antigen 125 was positively correlated with pro-brain natriuretic peptide in non-small cell lung cancer postoperative patients (p=0.00035). Univariate analysis did not find significant difference in disease progression survival between those who experienced cancer antigen 125 elevation in the early postoperation and those who did not (p=0.646).

CONCLUSIONS:

In conclusion, transient elevation of cancer antigen 125 is associated to pro-brain natriuretic peptide increase after pulmonary surgery in non-small cell lung cancer patients.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2021 Type: Article Affiliation country: China Institution/Affiliation country: Peking University Shenzhen Hospital/CN

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Full text: Available Index: LILACS (Americas) Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2021 Type: Article Affiliation country: China Institution/Affiliation country: Peking University Shenzhen Hospital/CN