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Potential impact of the COVID-19 in HIV-infected individuals: a systematic review Impact of the COVID-19 in HIV-Infected Individuals
de Medeiros, Kleyton Santos; da Silva, Luís Antônio Soares; Macêdo, Luíza Thomé de Araújo; Sarmento, Ayane Cristine; Costa, Ana Paula Ferreira; Eleutério Jr, José; Gonçalves, Ana Katherine.
  • de Medeiros, Kleyton Santos; Universidade Federal do Rio Grande do Norte. Health Sciences Postgraduate Program. Natal. BR
  • da Silva, Luís Antônio Soares; Centro Universitário do Rio Grande do Norte. Natal. BR
  • Macêdo, Luíza Thomé de Araújo; Centro Universitário do Rio Grande do Norte. Natal. BR
  • Sarmento, Ayane Cristine; Universidade Federal do Rio Grande do Norte. Health Sciences Postgraduate Program. Natal. BR
  • Costa, Ana Paula Ferreira; Universidade Federal do Rio Grande do Norte. Health Sciences Postgraduate Program. Natal. BR
  • Eleutério Jr, José; Universidade Federal do Ceará. Department of Obstetrics and Gynaecology. Fortaleza. BR
  • Gonçalves, Ana Katherine; Universidade Federal do Rio Grande do Norte. Health Sciences Postgraduate Program. Natal. BR
Rev. Assoc. Med. Bras. (1992) ; 67(supl.1): 127-156, 2021. tab, graf
Article in English | LILACS | ID: biblio-1287836
ABSTRACT
SUMMARY

BACKGROUND:

Although much has been studied about the SARS-Cov-2 virus, its effects, and the effectiveness of possible treatments, little is known about its interaction with other infectious diseases.

OBJECTIVE:

The aim is to study its clinical features and morbidity, and mortality outcomes of COVID-19 patients with HIV/AIDS coinfection. DATA SOURCES MEDLINE, Web of Science, Embase, CINAHL, LILACS, Scopus, ClinicalTrials.gov, and Cochrane. STUDY ELIGIBILITY CRITERIA Atudies in any language, published after 2019, were describing COVID-19 patients with HIV/AIDS. STUDY APPRAISAL JBI Levels of Evidence, Joanna Briggs Institute. SYNTHESIS

METHODS:

As shown in the PRISMA flow diagram, two authors separately screened the search results from the obtained titles and abstracts.

RESULTS:

Chest CT was observed in patients with pneumonia by SARS-CoV-2 with findings of multiple ground-glass opacities (GGO) in the lungs, there is a need for supplemental oxygenation. One patient developed encephalopathy and complicated tonic-clonic seizures; four patients were transplanted (two, liver; two, kidneys), one patient developed severe SARS-CoV-2 pneumonia and 30 patients died (mortality rate, 11%).

CONCLUSION:

HIV did not show any relevance directly with the occurrence of COVID-19. Some studies suggest that HIV-1 infection through induction levels of IFN-I, may to some extent, stop the apparent SARS-CoV-2 infection, thus leading to undetectable RNA. Moreover, some authors suggest retroviral therapy routinely used to control HIV infection could be used to prevent COVID-19 infection.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: HIV Infections / Coinfection / COVID-19 Type of study: Systematic reviews Limits: Humans Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Centro Universitário do Rio Grande do Norte/BR / Universidade Federal do Ceará/BR / Universidade Federal do Rio Grande do Norte/BR

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Full text: Available Index: LILACS (Americas) Main subject: HIV Infections / Coinfection / COVID-19 Type of study: Systematic reviews Limits: Humans Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Centro Universitário do Rio Grande do Norte/BR / Universidade Federal do Ceará/BR / Universidade Federal do Rio Grande do Norte/BR