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Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
Costa, Denise Maria do Nascimento; Laboratório de Imunopatologia Keizo AsamiCoêlho, Maria Rosângela Cunha Duarte; Gouveia, Pedro Alves da Cruz; Laboratório de Imunopatologia Keizo AsamiBezerra, Luan Araújo; Marques, Claudia Diniz Lopes; Duarte, Angela Luzia Branco Pinto; Valente, Lucila Maria; Magalhães, Vera.
  • Costa, Denise Maria do Nascimento; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
  • Laboratório de Imunopatologia Keizo AsamiCoêlho, Maria Rosângela Cunha Duarte; Universidade Federal de Pernambuco. Departamento de Virologia. Laboratório de Imunopatologia Keizo AsamiCoêlho, Maria Rosângela Cunha Duarte. Recife. BR
  • Gouveia, Pedro Alves da Cruz; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
  • Laboratório de Imunopatologia Keizo AsamiBezerra, Luan Araújo; Universidade Federal de Pernambuco. Departamento de Virologia. Laboratório de Imunopatologia Keizo AsamiBezerra, Luan Araújo. Recife. BR
  • Marques, Claudia Diniz Lopes; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
  • Duarte, Angela Luzia Branco Pinto; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
  • Valente, Lucila Maria; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
  • Magalhães, Vera; Universidade Federal de Pernambuco. Hospital das Clínicas. Recife. BR
Rev. Soc. Bras. Med. Trop ; 54: e08552021, 2021. tab
Article in English | LILACS | ID: biblio-1288089
ABSTRACT
Abstract The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection.
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Full text: Available Index: LILACS (Americas) Main subject: Chikungunya virus / Chikungunya Fever Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Pernambuco/BR

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Full text: Available Index: LILACS (Americas) Main subject: Chikungunya virus / Chikungunya Fever Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Pernambuco/BR