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Are overweight and obesity risk factors for invasive mechanical ventilation in severe coronavirus disease 2019 pneumonia?
Coss-Rovirosa, Maria Fernanda; Aguilar-Soto, Mercedes; Cuenca, Dalia; Velez-Pintado, Mariana; Camiro-Zuñiga, Antonio; Ferreira-Hermosillo, Aldo; Mercado, Moises.
  • Coss-Rovirosa, Maria Fernanda; American British Cowdray Medical Center. Department of Internal Medicine. Mexico City. MX
  • Aguilar-Soto, Mercedes; American British Cowdray Medical Center. Department of Internal Medicine. Mexico City. MX
  • Cuenca, Dalia; American British Cowdray Medical Center. Department of Internal Medicine. Mexico City. MX
  • Velez-Pintado, Mariana; American British Cowdray Medical Center. Department of Internal Medicine. Mexico City. MX
  • Camiro-Zuñiga, Antonio; American British Cowdray Medical Center. Department of Internal Medicine. Mexico City. MX
  • Ferreira-Hermosillo, Aldo; Instituto Mexicano del Seguro Social. Centro Médico Nacional Siglo XXI. Hospital de Especialidades. Mexico City. MX
  • Mercado, Moises; Instituto Mexicano del Seguro Social. Centro Médico Nacional Siglo XXI. Hospital de Especialidades. Mexico City. MX
Arch. endocrinol. metab. (Online) ; 65(4): 462-467, July-Aug. 2021. tab
Article in English | LILACS | ID: biblio-1339106
ABSTRACT
ABSTRACT

Objective:

Describe the demographic, clinical, and biochemical characteristics of overweight or obese people with severe COVID-19 pneumonia and evaluate its association with mechanical ventilation requirements in a Mexican cohort. Subjects and

methods:

Data were obtained from medical electronic records. Patients were divided in three groups according to the World Health Organization (WHO) classification of body mass index (BMI) lean, overweight and obese. Baseline characteristics and clinical course were compared among these 3 groups.

Results:

The study included a total of 355 patients with confirmed COVID-19 diagnoses. Patients with obesity and overweigh, according to the WHO classification, had no significantly increased risk of requiring intubation and invasive mechanical ventilation (IMV) compared to lean subjects, with an odds ratio (OR) of 1.82 (95% CI, 0.94-3.53). A post hoc and multivariate analysis using a BMI > 35 kg/m2 to define obesity revealed that subjects above this cut off had as significantly increased risk of requiring IMV after with an OR of 2.86 (95% CI, 1.09-7.05).

Conclusion:

We found no higher risk of requiring IMV in patients with overweight or obesity while using conventional BMI cutoffs. According to our sensitivity analyses, the risk of IMV increases in patients with a BMI over 35 kg/m2.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Respiration, Artificial / COVID-19 Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2021 Type: Article Affiliation country: Mexico Institution/Affiliation country: American British Cowdray Medical Center/MX / Instituto Mexicano del Seguro Social/MX

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Full text: Available Index: LILACS (Americas) Main subject: Respiration, Artificial / COVID-19 Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2021 Type: Article Affiliation country: Mexico Institution/Affiliation country: American British Cowdray Medical Center/MX / Instituto Mexicano del Seguro Social/MX