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Mantle cell lymphoma presenting with lethal atraumatic splenic rupture
Eyerer, Frederick; Gardner, Juli-Anne; Devitt, Katherine A.
Affiliation
  • Eyerer, Frederick; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US
  • Gardner, Juli-Anne; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US
  • Devitt, Katherine A; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US
Autops. Case Rep ; 11: e2021340, 2021. graf
Article in En | LILACS | ID: biblio-1345359
Responsible library: BR26.7
ABSTRACT
Mantle cell lymphoma is characterized by t(11;14) with CCND1-IGH fusion and manifests with a spectrum of disease ranging from relatively indolent to aggressive. Here, we present a case of pleomorphic mantle cell lymphoma with three fusion signals that presented with lethal atraumatic splenic rupture. We discuss on the implications of variant CCND1 signal patterns as well as the epidemiology and pathophysiology of atraumatic splenic rupture.
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Full text: 1 Index: LILACS Main subject: Splenic Rupture / Lymphoma, Mantle-Cell Limits: Aged / Humans / Male Language: En Journal: Autops. Case Rep / Autopsy and Case Reports Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article
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Full text: 1 Index: LILACS Main subject: Splenic Rupture / Lymphoma, Mantle-Cell Limits: Aged / Humans / Male Language: En Journal: Autops. Case Rep / Autopsy and Case Reports Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article