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Optimal Cutoff of the TG/HDL-c ratio for Cardiovascular Risk in Hypertensive and Diabetic Patients Monitored by Primary Health Care in a city in Minas Gerais
Silva, Eunice Ferreira da; Cotta, Rosângela Minardi Mitre; Mendonça, Érica Toledo; Oliveira, Deíse Moura de; Cardoso, Silvia Almeida; Colodette, Renata Maria; Moreira, Tiago Ricardo.
  • Silva, Eunice Ferreira da; Universidade Federal de Viçosa. Viçosa. BR
  • Cotta, Rosângela Minardi Mitre; Universidade Federal de Viçosa. Viçosa. BR
  • Mendonça, Érica Toledo; Universidade Federal de Viçosa. Viçosa. BR
  • Oliveira, Deíse Moura de; Universidade Federal de Viçosa. Viçosa. BR
  • Cardoso, Silvia Almeida; Universidade Federal de Viçosa. Viçosa. BR
  • Colodette, Renata Maria; Fundação Oswaldo Cruz. Rio de Janeiro. BR
  • Moreira, Tiago Ricardo; Universidade Federal de Viçosa. Viçosa. BR
Int. j. cardiovasc. sci. (Impr.) ; 34(5,supl.1): 55-65, Nov. 2021. tab, graf
Article in English | LILACS | ID: biblio-1346339
ABSTRACT
Abstract Background The analysis of the atherogenic potential of the lipid profile for biomarkers, such as the TG/HDL-c ratio, predicts cardiovascular risk better than isolated lipids. Objective To identify the TG/HDL-c cutoff points for multiple risks (hypertension, Diabetes Mellitus, obesity) and to evaluate the association between sociodemographic, clinical, laboratory, anthropometric, and life habit variables and the TG/HDL-c ratio in hypertensive and/or diabetic individuals in the context of Primary Health Care. Methods This was a cross-sectional study with 833 hypertensive and/or diabetic patients, conducted between August 2017 and April 2018. The cutoff point of the TG/HDL-c were obtained by the ROC curve. Cardiovascular risk was discriminated by TG/HDL-c, categorized by the cutoff and evaluated in relation to multiple risks. The magnitude of the association between TG/HDL-c and independent variables was estimated by logistic regression. The significance level of p<0.05 was adopted for all tests. Results The cutoff values of TG/HDL-c (3.26 for men and 2.72 for women) were more sensitive and less specific than those in the literature. Women (OR=1.90 and 95% CI 1.13-3.20) and men (OR=4.58 and 95% CI 1.78-11.76) with multiple risks, and white men, alcohol users, with a history of stroke, had a higher chance of altered GT/HDL-c. Increases in glycosylated hemoglobin, glycemia, and phosphorus in women, and cholesterol, glycemia, and microalbuminuria in men increased the chances of altered TG/HDL-c. Being a former smoker and black reduced the chance of altered TG/HDL-c in women. Conclusions TG/HDL-c proved to be a good indicator for habitual use in Primary Care.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Primary Health Care / Triglycerides / Heart Disease Risk Factors / Cholesterol, HDL Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Oswaldo Cruz/BR / Universidade Federal de Viçosa/BR

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Full text: Available Index: LILACS (Americas) Main subject: Primary Health Care / Triglycerides / Heart Disease Risk Factors / Cholesterol, HDL Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Oswaldo Cruz/BR / Universidade Federal de Viçosa/BR