The sum of kidney donor profile index and estimated post-transplant survival scale and their correlation with egfr decline in deceased donor kidney recipients
Rev. invest. clín
;
73(4): 216-221, Jul.-Aug. 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1347567
ABSTRACT
Background:
The impact of donor quality on post-kidney transplant survival may vary by candidate condition.Objective:
Analyzing the combined use of the Kidney Donor Profile Index (KDPI) and the estimated post-transplant survival (EPTS) scale and their correlation with the estimated glomerular filtration rate (eGFR) decline in deceased-donor kidney recipients (DDKR).Methods:
This was a retrospective, observational cohort study. We included DDKRs between 2015 and 2017 at a national third-level hospital.Results:
We analyzed 68 DDKR. The mean age at transplant was 41 ± 14 years, 47 (69%) had sensitization events, 18 (26%) had delayed graft function, and 16 (23%) acute rejection. The graft survival at 12 and 36 months was 98.1% (95% CI 94-100) and 83.7% (95% CI 65-100), respectively. The Pearson correlation coefficient between the percentage reduction in the annual eGFR and the sum of EPTS and KDPI scales was r = 0.61, p < 0.001. The correlation coefficient between the percentage reduction in the annual eGFR and the EPTS and KDPI scales separately was r = 0.55, p < 0.001, and r = 0.53, p < 0.001, respectively.Conclusions:
The sum of EPTS and KDPI scales can provide a better donor-recipient relationship and has a moderately positive correlation with the decrease in eGFR in DDKR.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tissue Donors
/
Kidney Transplantation
/
Graft Survival
Type of study:
Observational study
Limits:
Adult
/
Humans
Language:
English
Journal:
Rev. invest. clín
Journal subject:
Medicine
Year:
2021
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Civil Hospital of Guadalajara Fray Antonio Alcalde/MX
/
Institute for Social Security and Services for State Workers/MX
/
University of Guadalajara/MX
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