Bilateral hearing loss as an initial presentation of Creutzfeldt-Jakob disease / Perda auditiva bilateral como uma apresentação inicial da doença de creutzfeldt-jakob
Dement. neuropsychol
;
15(4): 548-549, Oct.-Dec. 2021. graf, il
Article
in English
| LILACS
| ID: biblio-1350690
ABSTRACT
ABSTRACT. We reported a case of a 61-year-old male patient with anacusis, cerebellar syndrome, myoclonus, and frontal signs. The brain magnetic resonance imaging showed bilateral striated hyperintensity of the fluid-attenuated inversion recovery and restricted diffusion in the diffusion-weighted imaging and hypointense areas corresponding to the apparent diffusion coefficient in the cerebral cortex. The autopsy revealed positive immunohistochemistry for the PrPSc protein. Creutzfeldt-Jakob disease presenting with hearing loss is unusual.
RESUMO
RESUMO. Relatamos o caso de um paciente do sexo masculino, 61 anos, com anacusia, síndrome cerebelar, mioclonia e sinais frontais. A ressonância magnética cerebral mostrou hiperintensidade estriada bilateral do fluid-attenuated inversion recovery (FLAIR) e difusão restrita no diffusion-weighted imaging (DWI) e áreas hipointensas correspondendo ao coeficiente de difusão aparente no córtex cerebral. A autópsia revelou imuno-histoquímica positiva para a proteína PrPSc. A doença de Creutzfeldt-Jakob que se apresenta com perda auditiva é incomum.
Full text:
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Index:
LILACS (Americas)
Main subject:
Creutzfeldt-Jakob Syndrome
Limits:
Humans
/
Male
Language:
English
Journal:
Dement. neuropsychol
Journal subject:
NEUROCIENCIAS
/
Neurology
/
Psychology
/
Psychiatry
Year:
2021
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Department of Neurology, Hospital Universitário Oswaldo Cruz/BR
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