Population-level seropositivity trend for SARS-Cov-2 in Rio Grande do Sul, Brazil
Rev. saúde pública (Online)
;
55: 1-11, 2021. tab, graf
Article
in English
| LILACS, BBO
| ID: biblio-1352161
ABSTRACT
ABSTRACT OBJECTIVE To describe the evolution of seropositivity in the State of Rio Grande do Sul, Brazil, through 10 consecutive surveys conducted between April 2020 and April 2021. METHODS Nine cities covering all regions of the State were studied, 500 households in each city. One resident in each household was randomly selected for testing. In survey rounds 1-8 we used the rapid WONDFO SARS-CoV-2 Antibody Test (Wondfo Biotech Co., Guangzhou, China). In rounds 9-10, we used a direct ELISA test that identifies IgG to the viral S protein (S-UFRJ). In terms of social distancing, individuals were asked three questions, from which we generated an exposure score using principal components analysis. RESULTS Antibody prevalence in early April 2020 was 0.07%, increasing to 10.0% in February 2021, and to 18.2% in April 2021. In round 10, self-reported whites showed the lowest seroprevalence (17.3%), while indigenous individuals presented the highest (44.4%). Seropositivity increased by 40% when comparing the most with the least exposed. CONCLUSIONS The proportion of the population already infected by SARS-Cov-2 in the state is still far from any perspective of herd immunity and the infection affects population groups in very different levels.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. saúde pública (Online)
Journal subject:
Sa£de P£blica
Year:
2021
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Fundação Getúlio Vargas/BR
/
The Rockefeller University/US
/
Universidade Federal da Fronteira Sul/BR
/
Universidade Federal de Ciências da Saúde de Porto Alegre/BR
/
Universidade Federal de Pelotas/BR
/
Universidade Federal de Santa Maria/BR
/
Universidade Federal do Pampa/BR
/
Universidade Regional do Noroeste do Estado do Rio Grande do Sul/BR
/
Universidade de Caxias do Sul/BR
/
Universidade de Santa Cruz do Sul/BR
Similar
MEDLINE
...
LILACS
LIS