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Evolução das manifestações clínicas de pacientes com doença de parkinson / Evolution of clinical manifestations of parkinson's disease patients
Lunardi, Mariana dos Santos; Oliveira, André Dias de; Freitas, Fernando Cini.
  • Lunardi, Mariana dos Santos; Universidade Federal de Santa Catarina. Hospital Governador Celso Ramos. Florianópolis. BR
  • Oliveira, André Dias de; EBSERH-HU. Florianópolis. BR
  • Freitas, Fernando Cini; Universidade Federal de Santa Catarina. Hospital Governador Celso Ramos. Florianópolis. BR
ACM arq. catarin. med ; 49(4): 41-54, 03/02/2021.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1354392
RESUMO

Objetivos:

Avaliar o perfil clínico e epidemiológico dos pacientes parkinsonianos acompanhados no ambulatório de Distúrbios do Movimento do Hospital Governador Celso Ramos utilizando-se escaladas validadas.

Métodos:

Estudo longitudinal onde foram incluídos 167 pacientes consecutivos, em diferentes estágios da doença de Parkinson, atendidos no ambulatório de distúrbios do movimento do HGCR e reavaliados 20 pacientes em consulta, 5 anos após a primeira. Aplicou-se questionário e avaliou-se o primeiro sintoma motor cardinal entre as associações independentes e entre os escores de sintomas neurológicos motores avaliados através da escala UPDRS-MDS e Schwab and England Activities of Daily Living Scale.

Resultados:

Tremor foi o primeiro sintoma motor percebido mais frequentemente pelos pacientes (64,9%), dor foi a primeira queixa de 5,2% dos pacientes. A idade de início do primeiro sintoma foi inversamente proporcional à escolaridade. Quanto maior a pontuação nas escalar UPDRS-MDS ­ III (p=0,004) e Schwab and England Activities of Daily Living Scale (p=0,001) maior a tendência a inatividade.

Conclusão:

A doença de Parkinson geralmente é percebida por seus sintomas motores clássicos, entretanto, uma série de sintomas não motores iniciam e acompanham a evolução da doença conforme mostra a piora do perfil ao longo de 5 anos.
ABSTRACT

Objectives:

To evaluate symptoms, establish a profile for the Parkinsonian patient of HGCR's Movement Disorders's Service.

Method:

Longitudinal study. 167 consecutive patients, in different stages of Parkinson's disease, and treated at HGCR movement disorders service were inclueded. 20 of them were reevaluated after 5 yers. A questionnaire was administered and the first cardinal motor symptoms was evaluated and associated with independent associations and with the scores of neurological symptoms measured by UPDRS-MDS and through the Schwab and England Activities of Daily Living Scale.

Results:

Tremor was the first motor symptom perceived most frequently by patients (64.9%), pain was the first complaint of 5,2% of patients. The age of onset of the first symptom was inversely proportional to schooling. The higher the scores in the UPDRS-MDS-III scale (p=0,004) and the Schwab and England Activities of the Daily Living Scale (p = 0,001) the greater the tendency to inactivity.

Conclusion:

Parkinson's disease is usually noticed by its classic motor symptoms, however, a series of non-motor symptoms begin and accompany the disease's progression. This study evaluated the profile of the clinical and epidemiological patients attending our service and showed important clinical worsening in the evolution of 5 years of disease.

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Index: LILACS (Americas) Type of study: Observational study / Risk factors Language: Portuguese Journal: ACM arq. catarin. med Journal subject: Medicine Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: EBSERH-HU/BR / Universidade Federal de Santa Catarina/BR

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Index: LILACS (Americas) Type of study: Observational study / Risk factors Language: Portuguese Journal: ACM arq. catarin. med Journal subject: Medicine Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: EBSERH-HU/BR / Universidade Federal de Santa Catarina/BR