Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment
Int. braz. j. urol
;
48(1): 31-51, Jan.-Feb. 2022. tab, graf
Article
in English
| LILACS
| ID: biblio-1356283
ABSTRACT
ABSTRACT Introduction:
Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. The aim of this document is to update issues on medical management of neurogenic bladder in children. Materials andMethods:
Five Pediatric Urologists joined a group of experts and reviewed all important issues on "Spina Bifida, Neurogenic Bladder in Children" and elaborated a draft of the document. All the members of the group focused on the same system of classification of the levels of evidence (GRADE system) in order to assess the literature and the recommendations. During the year 2020 the panel of experts has met virtually to review, discuss and write a consensus document. Results andDiscussion:
The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies. Clean intermittent catheterization (CIC) should be implemented during the first days of life, and antimuscarinic drugs should be indicated upon results of urodynamic studies. When the patient becomes refractory to first-line therapy, receptor-selective pharmacotherapy is available nowadays, which leads to a reduction in reconstructive procedures, such as augmentation cystoplasty.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Urinary Bladder, Neurogenic
/
Spinal Dysraphism
/
Meningomyelocele
/
Intermittent Urethral Catheterization
Type of study:
Practice guideline
Limits:
Child
/
Humans
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2022
Type:
Article
Affiliation country:
Argentina
/
Brazil
/
Chile
Institution/Affiliation country:
Hospital Roberto del Rio/CL
/
Italian Hospital/AR
/
National Hospital of Pediatrics/AR
/
Universidade Federal da Bahia - UFBA/BR
/
Universidade Federal de Juiz de Fora - UFJF/BR
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