Prolonged SARS-CoV-2 RNA shedding in a young man recovering from traumatic pneumothorax
S. Afr. med. j
;
112(2): 81-85, 2022.
Article
in English
| AIM
| ID: biblio-1358373
ABSTRACT
We describe a case of prolonged SARS-CoV-2 RNA shedding in an HIV-negative 21-year-old man recovering from abdominal and thoracic trauma. Nasopharyngeal (NP) swabs collected at 12 time points over a 95-day span all tested positive for SARS-CoV-2 by reverse transcription polymerase chain reaction (RT-PCR). Genotyping revealed canonical beta-variant E484K and N501Y mutations at earlier time points. Human rhinovirus, coronavirus NL63 and respiratory syncytial virus B were detected at different time points by RT-PCR. Full blood analysis at time point 9 (day 82) showed leukopenia with lymphocytosis. The patient's NP swab tested negative for SARS-CoV-2 by RT-PCR 101 days after the first positive test. The prolonged duration of SARS-CoV-2 RNA shedding in the context of trauma presented here is unique and has important implications for COVID-19 diagnosis, management and policy guidelines
Full text:
Available
Index:
AIM (Africa)
Main subject:
Pneumothorax
/
COVID-19 Nucleic Acid Testing
/
SARS-CoV-2
/
COVID-19
Type of study:
Practice guideline
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
S. Afr. med. j
Year:
2022
Type:
Article
Institution/Affiliation country:
Ndlovu Laboratories, Elandsdoorn/ZA
/
Ndlovu Laboratories, Elandsdoorn, Limpopo Province/ZA
/
Ndlovu Research Consortium, Elandsdoorn/ZA
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