Your browser doesn't support javascript.
loading
Skin manifestations associated with COVID-19
Seque, Camila Arai; Enokihara, Milvia Maria Simões e Silva; Porro, Adriana Maria; Tomimori, Jane.
  • Seque, Camila Arai; Universidade Federal de São Paulo. Department of Dermatology. São Paulo. BR
  • Enokihara, Milvia Maria Simões e Silva; Universidade Federal de São Paulo. Department of Dermatology. São Paulo. BR
  • Porro, Adriana Maria; Universidade Federal de São Paulo. Department of Dermatology. São Paulo. BR
  • Tomimori, Jane; Universidade Federal de São Paulo. Department of Dermatology. São Paulo. BR
An. bras. dermatol ; 97(1): 75-88, Jan.-Feb. 2022. tab, graf
Article in English | LILACS | ID: biblio-1360077
ABSTRACT
Abstract This article will address the main aspects of skin manifestations associated with COVID-19, based on a review of the literature published to date. Since the beginning of the pandemic, more than 1,500 articles have been published on the subject. Regarding the pathophysiology, it is believed that the same mechanisms responsible for the disease in the main target organs also act in the skin, although they are not yet fully elucidated. The actual frequency of dermatological manifestations remains uncertain - it can range from 0.2% to 45%, being close to 6% in systematic reviews. Pioneering studies of large case series conducted in European countries and the USA provide the first information on the main skin manifestations associated with COVID-19 and propose classifications regarding their clinical presentation, pathophysiology, as well as their frequencies. Although there is yet no consensus, maculopapular eruptions are considered the most frequent presentations, followed by erythema pernio-like (EPL) lesions. Manifestations such as urticaria, vesicular conditions and livedo/purpura/necrosis are rare. The time of onset, severity, need for specific treatment and prognosis vary according to the clinical presentation pattern. The increasing histopathological description of skin conditions can contribute to the diagnosis, as well as to the understanding of the pathophysiology. Also, in the dermatological field, the relationship between COVID-19 and androgens has been increasingly studied. Despite all the generated knowledge, the actual biological meaning of skin manifestations remains uncertain. Therefore, the exclusion of the main differential diagnoses is essential for the correlation between skin manifestation and COVID-19.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Skin Diseases / COVID-19 Type of study: Prognostic study / Risk factors / Systematic reviews Limits: Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Skin Diseases / COVID-19 Type of study: Prognostic study / Risk factors / Systematic reviews Limits: Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR