Brain Tumor Heterogeneity
Arq. bras. neurocir
;
40(3): 253-256, 15/09/2021.
Article
in English
| LILACS
| ID: biblio-1362147
ABSTRACT
Tumor heterogeneity is the concept that different tumor cells provide distinct biomorphological lesions, gene expressions, proliferation, microenvironment and graduated capacity of metastatic lesions. Brain tumor heterogeneity has been recently discussed about the interesting interaction of chronic inflammation, microenvironment, epigenetics and glioma steam cells. Brain tumors remain a challenge with regards to medication and disease, due to the lack of treatment options and unsatisfactory results. These results might be the result of the brain tumor heterogeneity and its multiple resistance mechanisms to chemo and radiotherapy.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Neoplastic Stem Cells
/
Brain Neoplasms
/
Genetic Heterogeneity
/
Gene Expression Profiling
/
Glioma
Language:
English
Journal:
Arq. bras. neurocir
Journal subject:
Cirurgia
/
Neurosurgery
Year:
2021
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Pontifícia Universidade Católica de Campinas/BR
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