Your browser doesn't support javascript.
loading
Analysis of potential drug interactions in medical clinic sector in a Hospital of João Pessoa - PB
Costa, Jéssyca Pinheiro da; Alves, Gislayne Azevedo de Campos; Guedes, Érika da Cruz; Fonseca, Flávia Pessoa de Belmont; Souto, Rosa Águida Donosora de Melo; Lopes, Pablo Queiroz; Golzio, Adriana Maria Fernandes de Oliveira.
  • Costa, Jéssyca Pinheiro da; Federal University of Paraiba. Health Sciences Center. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Alves, Gislayne Azevedo de Campos; Federal University of Paraiba. Lauro Wanderley University Hospital. Brazilian Company of Hospital Services. João Pessoa. BR
  • Guedes, Érika da Cruz; Federal University of Paraiba. Bioactive Natural and Synthetic Products Program. João Pessoa. BR
  • Fonseca, Flávia Pessoa de Belmont; Federal University of Paraiba. Lauro Wanderley University Hospital. João Pessoa. BR
  • Souto, Rosa Águida Donosora de Melo; Federal University of Paraiba. Lauro Wanderley University Hospital. João Pessoa. BR
  • Lopes, Pablo Queiroz; Federal University of Paraiba. Health Sciences Center. Department of Pharmaceutical Sciences. João Pessoa. BR
  • Golzio, Adriana Maria Fernandes de Oliveira; Federal University of Paraiba. Center of Technology and Regional Development. Department of Food Technology. João Pessoa. BR
Braz. J. Pharm. Sci. (Online) ; 58: e18943, 2022. graf
Article in English | LILACS | ID: biblio-1364427
ABSTRACT
Abstract The objective of this study was to evaluate drug interactions based on medical records of patients hospitalized in University Hospital Lauro Wanderley (UHLW) in João Pessoa-PB, Brazil. This was a quantitative, descriptive study with a cross-sectional design. This research was conducted in the medical clinic of the above hospital by analyzing pharmaceutical intervention in medical records. The investigated samples consisted of all medical profiles with drug interaction information of patients hospitalized from June 2016 to June 2017. Most of these drug interactions were determined and classified by Micromedex® Solutions database. This research was approved by the Ethics Committee in Institutional Human Research, protocol number 2.460.206. In total, 331 drug interactions were found in 131 medical profiles. Dipyrone, enoxaparin, sertraline, ondansetron, quetiapine, tramadol, bromopride, amitriptyline, and simvastatin were medications that showed highest interactions. According to Anatomical Therapy Classification (ATC), drugs that act on the central nervous system result in more interactions. The most prevalent interaction was between dipyrone and enoxaparin. Some limitations of this study are the lack of notifications and data on drug interactions.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Research / Medical Records / Drug Interactions / Evaluation Studies as Topic / Inpatients Type of study: Diagnostic study / Evaluation studies / Practice guideline Limits: Female / Humans / Male Language: English Journal: Braz. J. Pharm. Sci. (Online) Journal subject: Farmacologia / Terapˆutica / Toxicologia Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Paraiba/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Research / Medical Records / Drug Interactions / Evaluation Studies as Topic / Inpatients Type of study: Diagnostic study / Evaluation studies / Practice guideline Limits: Female / Humans / Male Language: English Journal: Braz. J. Pharm. Sci. (Online) Journal subject: Farmacologia / Terapˆutica / Toxicologia Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Paraiba/BR