Profundidad de la línea de demarcación del estroma corneal después de la reticulación del colágeno corneal usando epitelial corneal personalizado versus convencional desbridamiento / Corneal stromal demarcation line depth after corneal collagen cross-linking using customized versus conventional corneal epithelial debridement
Prensa méd. argent
; 106(7): 451-456, 20200000. graf
Article
in En
| LILACS, BINACIS
| ID: biblio-1366974
Responsible library:
AR392.1
ABSTRACT
Aim of the Study Compare the corneal demarcation line (DL) depth after corneal collagen cross-linking (CXL) with subtotal versus customized corneal epithelium debridement using anterior segment optical coherence tomography (AS-OCT). Design:
Prospective case-control study. Materials andMethods:
The study enrolled 18 patients with bilateral progressive keratoconus. Both eyes treated by CXL using 3 mW/cm2 / 30 minutes setting. One eye with subtotal epithelial debridement (about 9 mm diameter) and the contralateral eye with customized debridement (approximately 1 mm single horizontal central scratch). One month postoperatively, patients had AS-OCT imaging to detect and measure the depth ofDL.Results:
Patients' age mean was 25.17 years +/- 4.81 SD. Epithelial healing completed with in 3-7 days in conventional treatment group and demarcation line was evident in 16 eyes (89%) with a mean depth of 290.31 µm while in customized debridement group, the epithelial healing lasted less than 24 hours and DL was detectable in 10 patients (55.5 %) with a mean DL depth of 221 µm with a statistically significant difference (p < 0.05). Subjective postoperative pain graded as "moderate to severe" in about 77% of eyes underwent 9 mm epi-off CXL compared with 55% of those with customized debridement group.Conclusions:
Although the DL if found in majority cases, but the shallow location in customized corneal debridement cases questioned the efficacy of this technique despite the quick re-epithelialization and less postoperative pain that accompanied it
Full text:
1
Index:
LILACS
Main subject:
Collagen
/
Epithelium, Corneal
/
Corneal Stroma
/
Debridement
/
Tomography, Optical Coherence
/
Keratoconus
Type of study:
Observational_studies
Limits:
Adult
/
Humans
Language:
En
Journal:
Prensa méd. argent
Journal subject:
MEDICINA
Year:
2020
Type:
Article