Lípidos anormales e inmunidad adquirida Síndrome de Deficiencia: Asociación de Suero Lípidos con estatus de VIH / Abnormal Lipids and Acquired Immune Deficiency Syndrome: Association of Serum Lipids with HIV Status
Prensa méd. argent
;
106(6): 371-378, 20200000. tab, fig
Article
in English
| LILACS, BINACIS
| ID: biblio-1367088
ABSTRACT
Context and Aim:
Hematological abnormalities are amongst the most common complications of infection with HIV.There have been quite a few studies on the alterations in lipid profile, too, though the results have largely been inconclusive. The present study was carried-out to assess CD4 cell counts and lipid profile in the HIV infected and AIDS patients in the Indian population and correlates them with the sero-negative controls. Materials andMethods:
The present study was designed as a cross-sectional, hospital-based study to assess CD4 cell counts and lipid profile in the HIV infected and AIDS patients in the Indian population and correlates them with the sero-negative controls. Evaluation of lipid profile was done using Erba EM 360, an automated analyzer powered by a diffraction grating photometer while CD4 cell counts were evaluated using Partec Cyflow Counter. Statistical analysis used The data was analyzed using SPSS version 15.0 (SPSS Inc., Chicago, IL, USA). Comparison of the said parameters was done using Analysis of Variance (ANOVA) and posthoc Games-Howell test. p-value of <0.05 was considered statistically significant.Results:
The levels of total cholesterol and low-density lipoproteins (LDLs) were significantly decreased while triglycerides and very low density lipoproteins (VLDLs) were significantly increased in the HIV infected and AIDS patients when compared with the sero-negative controls.Conclusion:
Total cholesterol, LDLs, triglycerides and VLDLs were significantly altered in the HIV infected and AIDS patients when compared with the sero-negative controls.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
CD4 Antigens
/
HIV Infections
/
Cross-Sectional Studies
/
Analysis of Variance
/
HIV Seronegativity
/
Dyslipidemias
/
Lipids
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Prensa méd. argent
Journal subject:
Medicine
Year:
2020
Type:
Article
Affiliation country:
India
Institution/Affiliation country:
Associate Consultant-Cardiology/IN
/
Maharaja Agrasen Medical College/IN
/
Saraswati Dhanwantari Dental College and Hospital/IN
/
Sathyabama Dental College and Hospital/IN
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