Scanning electron microscopy of panitumumab-induced eyelash and hair alterations - Pili canaliculi
An. bras. dermatol
;
97(2): 240-242, Mar.-Apr. 2022. graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1374243
ABSTRACT
Abstract Panitumumab is a monoclonal antibody against the epidermal growth factor receptor used in metastatic colorectal cancer; in addition to tumor cells, it acts on epidermal keratinocytes and on the outer root sheath and presents skin toxicity in up to 90% of cases. A scanning electron microscope was used to examine the eyelashes and hairs of a 65-year-old patient with eyelash trichomegaly, curly hair, and paronychia undergoing treatment with panitumumab. Grooving in the hair shafts were identified, which were more evident in the eyelashes. Similar to oral epidermal growth factor inhibitors (erlotinib and gefitinib), panitumumab can cause acquired pili canaliculi.
Full text:
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Index:
LILACS (Americas)
Type of study:
Prognostic study
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Católica de Pelotas/BR
/
Universidade Federal de Pelotas/BR
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