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Preemptive analgesia with ibuprofen increases anesthetic efficacy in children with severe molar hypomineralization: a triple-blind randomized clinical trial
Vicioni-Marques, Fernanda; Paula-Silva, Francisco Wanderley Garcia de; Carvalho, Milena Rodrigues; Queiroz, Alexandra Mussolino de; Freitas, Osvaldo de; Duarte, Maíra Peres Ferreira; Manton, David John; Carvalho, Fabrício Kitazono de.
  • Vicioni-Marques, Fernanda; Universidade de São Paulo. Faculdade de Odontologia de Ribeirão Preto. Departamento de Odontopediatria. Ribeirão Preto. BR
  • Paula-Silva, Francisco Wanderley Garcia de; Universidade de São Paulo. Faculdade de Odontologia de Ribeirão Preto. Departamento de Odontopediatria. Ribeirão Preto. BR
  • Carvalho, Milena Rodrigues; Universidade de São Paulo. Faculdade de Odontologia de Ribeirão Preto. Departamento de Odontopediatria. Ribeirão Preto. BR
  • Queiroz, Alexandra Mussolino de; Universidade de São Paulo. Faculdade de Odontologia de Ribeirão Preto. Departamento de Odontopediatria. Ribeirão Preto. BR
  • Freitas, Osvaldo de; Universidade de São Paulo. Escola de Ciências Farmacêuticas de Ribeirão Preto São Paulo. Departamento de Ciências Farmacêuticas. BR
  • Duarte, Maíra Peres Ferreira; Universidade de São Paulo. Escola de Ciências Farmacêuticas de Ribeirão Preto São Paulo. Departamento de Ciências Farmacêuticas. BR
  • Manton, David John; University of Groningen. Faculty of Medical Sciences. Centrum voor Tandheelkunde en Mondzorgkunde. NL
  • Carvalho, Fabrício Kitazono de; Universidade de São Paulo. Escola de Ciências Farmacêuticas de Ribeirão Preto São Paulo. Departamento de Ciências Farmacêuticas. BR
J. appl. oral sci ; 30: e20210538, 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1375716
ABSTRACT
Abstract Molar incisor hypomineralization (MIH) is often accompanied by dental hypersensitivity and difficulty in achieving effective analgesia.

Objective:

This study evaluated the effectiveness of preemptive analgesia in children with severe MIH, post-eruptive enamel breakdown, and hypersensitivity.

Methodology:

Ibuprofen (10 mg/kg child weight) or placebo was administered, followed by infiltrative anesthesia and restoration with resin composite. Hypersensitivity was evaluated in five moments. The data were analyzed using the chi-square test, Fisher's exact test, and t-test.

Results:

Preemptive analgesia provided benefits for the treatment of severe cases of MIH, with an increase in the effectiveness of infiltrative anesthesia and improved patient comfort during the restorative procedure.

Conclusion:

Preemptive analgesia has shown efficacy in reducing hypersensitivity during restorative dental procedures, evidencing the significance of this study for patients with MIH and hypersensitivity.


Full text: Available Index: LILACS (Americas) Type of study: Controlled clinical trial Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2022 Type: Article Affiliation country: Brazil / Netherlands Institution/Affiliation country: Universidade de São Paulo/BR / University of Groningen/NL

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Full text: Available Index: LILACS (Americas) Type of study: Controlled clinical trial Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2022 Type: Article Affiliation country: Brazil / Netherlands Institution/Affiliation country: Universidade de São Paulo/BR / University of Groningen/NL