Effect of weekly versus daily primaquine on Plasmodium vivax malaria recurrences: A real-life cohort study
Rev. Soc. Bras. Med. Trop
;
55: e0738, 2022. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1376352
ABSTRACT
ABSTRACT Background:
Although primaquine (PQ) is indicated for G6PD-deficient patients, data on weekly PQ use in Brazil are limited.Methods:
We aimed to investigate malaria recurrences among participants receiving daily and weekly PQ treatments in a real-life setting of two municipalities in the Amazon between 2019 and 2020.Results:
Patients receiving weekly PQ treatment had a lower risk of recurrence than those receiving daily PQ treatment (risk ratio 0.62, 95% confidence interval 0.41-0.94), using a model adjusted for study site.Conclusions:
Weekly PQ use did not increase the risk of malaria recurrence. Further studies with larger populations are warranted.
Full text:
Available
Index:
LILACS (Americas)
Type of study:
Etiology study
/
Observational study
/
Risk factors
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2022
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado/BR
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