Vertebrobasilar circulation hemorrhages in childhood primary angiitis of the central nervous system
Autops. Case Rep
;
12: e2021391, 2022. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1383895
ABSTRACT
ABSTRACT Childhood primary angiitis of the CNS (cPACNS) is a poorly understood, rare, and diagnostically challenging neurologic disease. We describe an unusual and autopsy-confirmed case of cPACNS presenting as vertebrobasilar circulation hemorrhagic strokes in a 4-year-old girl. The presentation and clinical features were inconsistent with primary CNS vasculitis and skewed the diagnosis. Autopsy and histopathological analyses revealed a progressive lymphocytic vasculitis affecting the medium to large vessels of vertebrobasilar circulation and sparing the anterior circulation. It is imperative to raise the index of suspicion for cPACNS in any case of unusual or unexplained neurological presentation, especially in the absence of cerebrovascular risk factors and/or coagulation disorders.
Full text:
Available
Index:
LILACS (Americas)
Type of study:
Risk factors
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2022
Type:
Article
Affiliation country:
United kingdom
Institution/Affiliation country:
Addenbrookes Hospital/GB
Similar
MEDLINE
...
LILACS
LIS