Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study
Int. j interdiscip. dent. (Print)
;
15(1): 25-28, abr. 2022. tab, graf
Article
in English
| LILACS
| ID: biblio-1385244
ABSTRACT
ABSTRACT Background:
Recurrent aphthous stomatitis (RAS) is the most common oral ulceration. Its prevalence in the general population varies between 5% and 60%, and during the acute period, it causes pain and interferes with basic activities, such as eating, swallowing and talking. Dentoxol® is a medical mouthrinse that cleans, moisturizes and lubricates the mouth, mechanically stimulating local epithelial regeneration. The aim of this study was to evaluate the efficacy of Dentoxol® in improving the general state of patient with minor RAS using two different treatment schemes. Material andmethods:
Thirty-nine patients with RAS were recruited in a prospective observational pilot study. Two dosing regimens, 5 ml of Dentoxol® twice daily and 5 ml of Dentoxol® three times daily were evaluated.Results:
Efficacy to improve the general state was significant superior in "Three time daily" group compared with "twice daily" at 72 h (66% vs 33% respectively). No pain was reported in approximately 90% of cases at 96 h of use in both group without significant differences between the groups in any evaluation time-point.Conclusion:
Despite the limitations of these preliminary data, Dentoxol® shows promising beneficial properties for the management of minor RAS.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Stomatitis, Aphthous
/
Oral Ulcer
Type of study:
Risk factors
Limits:
Adolescent
/
Adult
/
Humans
Language:
English
Journal:
Int. j interdiscip. dent. (Print)
Journal subject:
Medicina Cl¡nica
/
Odontologia
/
Patologia
Year:
2022
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Ingalfarma SpA/CL
/
Universidad Mayor/CL
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