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The distribution and function of aquaporin 1 and 2 along the kidney in different species / Distribución y función de la acuaporina 1 y 2 a lo largo del riñón en diferentes especies
An, Fengli; Zhu, Shun.
  • An, Fengli; Lanzhou University. School of Pharmacy. Gansu. CN
  • Zhu, Shun; Suzhou Hua Jian Rui Da Pharmaceutical Technology Co. Jiangsu. CN
Int. j. morphol ; 39(3): 890-895, jun. 2021. ilus
Article in English | LILACS | ID: biblio-1385423
ABSTRACT

SUMMARY:

Water metabolism in kidney is critical for organisms living in arid environments. In this study, the kidney structure and the expression of AQP1 and AQP2 in Phrynocephalus vlangalii and Camelus bactrianus were studied. It was found that the Phrynocephalus vlangalii has fewer renal corpuscle but developed kidney tubules, and AQP1 and AQP2 were mainly expressed in the kidney tubules. Camelus bactrianus has a large diameter of glomerulus, thick bulbar membrane, and long and dense urinary tract. AQP1 was highly expressed in the proximal convoluted tubule, proximal straight tubule, and Ansa nephroni (Henle´s loop), and AQP2 was also highly expressed in the collecting tubule and distal convoluted tubule. In the long-term evolutionary adaptation, the morphological structure of animal kidney is consistent with its environment. In addition to structural and functional adaptation, aquaporin also participates in the adaptation to water scarcity environment, and may also play a key role.
RESUMEN
RESUMEN El metabolismo del agua en los riñones es fundamental para los organismos que viven en ambientes áridos. En este estudio, se estudió la estructura renal y la expresión de AQP1 y AQP2 en Phrynocephalus vlangalii y Camelus bactrianus. Se encontró que Phrynocephalus vlangalii tiene menos corpúsculos renales. pero desarrolló túbulos renales, y AQP1 y AQP2 se expresaron principalmente en los túbulos renales. Camelus bactrianus tiene un glomérulo de gran diámetro, una membrana bulbar gruesa y un tracto urinario largo y denso. AQP1 se expresó en gran medida en el túbulo contorneado proximal, el túbulo recto proximal y el Ansa nephroni o asa nefrónica (asa de Henle), y AQP2 también se expresó en gran medida en el túbulo colector y el túbulo contorneado distal. A largo plazo, en la adaptación evolutiva la estructura morfológica del riñón animal es coherente con su entorno. Además de la adaptación estructural y funcional, la acuaporina también es parte de la adaptación al entorno de escasez de agua y puede desempeñar un papel clave.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Camelus / Aquaporins / Kidney Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2021 Type: Article Affiliation country: China Institution/Affiliation country: Lanzhou University/CN / Suzhou Hua Jian Rui Da Pharmaceutical Technology Co/CN

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Full text: Available Index: LILACS (Americas) Main subject: Camelus / Aquaporins / Kidney Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2021 Type: Article Affiliation country: China Institution/Affiliation country: Lanzhou University/CN / Suzhou Hua Jian Rui Da Pharmaceutical Technology Co/CN