Recidiva intestinal única de melanoma cutáneo maligno: reporte de un caso / Intestinal relapse of a cutaneous melanoma: report of one case
Rev. méd. Chile
;
149(8): 1236-1240, ago. 2021. ilus
Article
in Spanish
| LILACS
| ID: biblio-1389575
ABSTRACT
Digestive tract primary melanoma is uncommon. However, metastatic lesions are more frequent and occur mainly in the small intestine. We report a 69-year-old male patient who consulted for a hyperpigmented skin lesion on the left thigh associated with multiple subcutaneous nodules. The biopsy was compatible with melanoma and PET/CT was positive for metastases in nodules and in an inguinal lymph node. Radiotherapy and chemotherapy with pembrolizumab were performed with good response, associated with posterior resection of the inguinal lymph node and melanocytic lesions. At three years of follow-up, a new hypermetabolic focus in the proximal jejunum was found in a control PET/CT. An endoscopic biopsy confirmed that it was a recurrence of the melanoma. Laparoscopic resection with primary anastomosis was performed with good clinical evolution. The definitive biopsy showed a melanoma metastasis with two of three lymph nodes positive for metastasis and a non-mutated BRAF gene. In conclusion, a single intestinal recurrence of melanoma is rare and requires an active search, since it can be resected using minimally invasive techniques.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin Neoplasms
/
Melanoma
Limits:
Aged
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2021
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Clínico Pontificia Universidad Católica/CL
/
Pontificia Universidad Católica de Chile/CL
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