Factores de riesgo de artrosis de rodilla, cadera o ambas en mujeres chilenas de mediana edad: un estudio de cohorte de tres décadas / Risk factors for the development of osteoarthritis in middle-aged women
Rev. méd. Chile
;
150(1): 46-53, ene. 2022. ilus, tab
Article
in Spanish
| LILACS
| ID: biblio-1389617
ABSTRACT
BACKGROUND:
Osteoarthritis (OA) is a health problem affecting millions of individuals worldwide.Aim:
To evaluate risk factors for hip and knee osteoarthritis (OA) in women aged 40 to 59 years. MATERIAL ANDMETHODS:
Analysis of a prospective cohort of 1159 women attending preventive health care programs and followed during 28 years. They underwent a clinical and laboratory evaluation from 1990 to 1993. The diagnosis of OA was retrieved from registries of a special program for osteoarthritis in 2020.RESULTS:
Twenty four percent of participants developed osteoarthritis during the follow-up. At the beginning of the study and compared with women without OA, they were older (median [interquartile range or IQR] 49.6 [8.5] and 47.2 [8.2] years respectively), had a higher body mass index (26.3 [5.3] and 25.1 [5.3] respectively), and a higher frequency of jobs with low qualification (76 and 62% respectively). The presence of type 2 diabetes mellitus, chronic hypertension, a previous history of alcohol or cigarette consumption, postmenopausal status and lipid and glucose blood levels did not differ between women with or without OA. Cox regression showed a final model that incorporates body mass index (hazard ratio (HR) 1.04; 95% confidence intervals (CI) 1.01-1.07), age (HR 1.05; 95% CI 1.03-1.08) and having an unqualified job (HR 1.88; 95% CI 1.43-2.47) as risk factors for OA.CONCLUSIONS:
Obesity and the type of job are the most relevant risk factors found for OD both may be modified with proper care.
Full text:
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Index:
LILACS (Americas)
Main subject:
Osteoarthritis, Hip
/
Osteoarthritis, Knee
/
Diabetes Mellitus, Type 2
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2022
Type:
Article
Affiliation country:
Chile
/
Ecuador
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
/
Universidad Católica de Santiago de Guayaquil/EC
/
Universidad Finis Terrae/CL
/
Universidad de Chile/CL
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