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Hipotiroidismo subclínico y pérdida de embarazo: una revisión de la literatura / Subclinical Hypothyroidism and Pregnancy Loss: A Literature Review
Mukhtar, Beenish; Garg, Rinku; Batra, Jyoti; Khan, Shaima Zafer; Khan, Mohammed Moizuddin.
  • Mukhtar, Beenish; Dar Al Uloom University. College of Medicine. Department of Physiology. Riyadh. SA
  • Garg, Rinku; Santosh Deemed to be University. Department of Physiology. Ghaziabad. IN
  • Batra, Jyoti; Santosh Deemed to be University. Ghaziabad. IN
  • Khan, Shaima Zafer; Dar Al Uloom Universit. College of Medicine. Department of Pharmacology. Riyadh. SA
  • Khan, Mohammed Moizuddin; Dar Al Uloom University. College of Medicine. Department of Physiology. Riyadh. SA
Prensa méd. argent ; 108(5): 270-276, 20220000.
Article in English | LILACS, BINACIS | ID: biblio-1392627
RESUMEN
Existe una alta prevalencia de hipotiroidismo subclínico (SCH) en el embarazo. Está vinculado a una importante morbilidad y mortalidad materna y fetal. Los efectos de SCH sobre el embarazo incluyen mayores riesgos de hipertensión gestacional y ruptura prematura de membranas (PROM). Sus fetos y bebés tenían más probabilidades de sufrir de bajo peso al nacer (LBW) y retraso del crecimiento intrauterino (IUGR). El riesgo de aborto espontáneo se informa alto en varios estudios para SCH no tratado. SCH se asocia directamente con una mayor presencia de anti -cuerpos anti TPO en suero materno. La detección temprana y el tratamiento de SCH han sido testigos de mejores resultados en términos de resultado del embarazo. Esta revisión se centra para establecer la relación de una mayor prevalencia de SCH en los países en desarrollo, así como su asociación con el aumento de los cuerpos anti TPO en suero materna y sacar una conclusión que puede ayudar a reducir las razones y proporcionar una solución. Este estudio concluyó que SCH es más frecuente en los países en desarrollo, ya sea debido a la deficiencia de yodo, una disminución de la conciencia sobre este problema o menos acceso a las instalaciones médicas. Por lo tanto, se sugiere que las hembras con antecedentes de partos prematuros, IUGR anteriores o abortos involuntarios deben someterse a una detección de hipotiroidismo subclínico y niveles de anticuerpos anti TPO durante sus visitas prenatales
ABSTRACT
There is a high prevalence of subclinical hypothyroidism (SCH) in pregnancy. It is linked to significant maternal and fetal morbidity and mortality. SCH's effects on pregnancy include increased risks of gestational hypertension and premature rupture of membranes (PROM). Their fetuses and infants had been more likely to suffer from low birth weight (LBW) and intrauterine growth retardation (IUGR). The risk of miscarriage is reported high in various studies for untreated SCH. SCH is directly associated with increased presence of anti TPO anti bodies in maternal serum. Early detection and treatment of SCH have witnessed better results in terms of pregnancy outcome. This review focuses to establish the relationship of increased prevalence of SCH in the developing countries as well as its association with increased anti TPO anti bodies in maternal serum and draw a conclusion which can help narrow down the reasons and provide solution. This study concluded that SCH is more prevalent in developing countries, either due to iodine deficiency, decreased awareness about this problem or less access to medical facilities. Therefore, it is suggested that females with history of preterm deliveries, previous IUGRs, or miscarriages should undergo screening for subclinical hypothyroidism and Anti TPO antibody levels during their antenatal visits.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Iodine Deficiency / Abortion, Spontaneous / Early Diagnosis / Hypertension, Pregnancy-Induced / Fetal Death / Maternal Death / Hyperthyroidism Type of study: Diagnostic study / Risk factors / Screening study Limits: Female / Humans / Pregnancy Language: English Journal: Prensa méd. argent Journal subject: Medicine Year: 2022 Type: Article Affiliation country: India / Saudi Arabia Institution/Affiliation country: Dar Al Uloom Universit/SA / Dar Al Uloom University/SA / Santosh Deemed to be University/IN

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Full text: Available Index: LILACS (Americas) Main subject: Iodine Deficiency / Abortion, Spontaneous / Early Diagnosis / Hypertension, Pregnancy-Induced / Fetal Death / Maternal Death / Hyperthyroidism Type of study: Diagnostic study / Risk factors / Screening study Limits: Female / Humans / Pregnancy Language: English Journal: Prensa méd. argent Journal subject: Medicine Year: 2022 Type: Article Affiliation country: India / Saudi Arabia Institution/Affiliation country: Dar Al Uloom Universit/SA / Dar Al Uloom University/SA / Santosh Deemed to be University/IN