Descripción de una cepa de Klebsiella pneumoniae con gen blaOXA-48 en Lima-Perú / Description of a Klebsiella pneumoniae strain with blaOXA-48 gene in Lima-Peru

RESUMEN

Señor editor La propagación de enterobacterales productoras de carbapenemasas se ha convertido en una importante amenaza para la salud mundial. El gen blaOXA-48 produce una carbapenemasa de clase "D" (según la clasificación de Ambler) que expresa un fenotipo resistente a penicilinas, penicilinas con inhibidores de beta-lactamasas, cefalosporinas de primera generación y sensibilidad reducida a los carbapenemes, sensibilidad reducida o casi nula a las cefalosporinas de amplio espectro.

ABSTRACT

Dear Editor The spread of carbapenemase-producing Enterobacteriaceae has become a major threat to global health. The blaOXA- gene blaOXA-48 produces a class "D" carbapenemase (according to Ambler's classification) that expresses a phenotype resistant to penicillins, penicillins with beta-lactamase inhibitors, first-generation cephalosporins and reduced sensitivity to carbapenems, reduced or near-zero sensitivity to broad-spectrum cephalosporins.48 produces a class "D" carbapenemase (according to Ambler's classification) that expresses a phenotype resistant to penicillins, penicillins with beta-lactamase inhibitors, first-generation cephalosporins and reduced sensitivity to carbapenems, reduced or near-zero sensitivity to broad-spectrum cephalosporins.