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Anemia megaloblástica. A propósito de un caso / Megaloblastic anemia
Cabrera Aguilar, Wendy; Mendoza Sánchez, Angela.
  • Cabrera Aguilar, Wendy; Caja Nacional de Salud. La Paz. BO
  • Mendoza Sánchez, Angela; Caja Nacional de Salud. La Paz. BO
Cuad. Hosp. Clín ; 63(1): 44-49, jun. 2022.
Article in Spanish | LILACS | ID: biblio-1399680
RESUMEN
La OMS reporta anemia en 24,8% de la población con predominio en países en desarrollo. La anemia megaloblástica, es una causa frecuente en la población adulta mayor. Se caracteriza por alteración en la síntesis de ácido desoxirribonucleico por deficiencia de vitamina B12 y/o folatos. Presentamos el caso de una mujer con manifestaciones clínicas y alteraciones de laboratorio características. Recibió tratamiento combinado con cianocobalamina y ácido fólico. Paulatinamente presentó reversión clínica y laboratorial. A pesar del nombre, la anemia megaloblástica, suele cursar con anemia, bicitopenia o ancitopenia y alteraciones sistémicas. Es obligatorio buscar la causa desencadenante para instaurar el tratamiento completo.
ABSTRACT
The WHO reports anemia in 24.8% of the population mainly in developing countries. Megaloblastic anemia is a frequent cause in the elderly population and it is due to an impaired synthesis of deoxyribonucleic acid. A deficiency of vitamin B12 and / or folic acid are the main causes. We present the case of a woman with characteristic clinical manifestations and laboratory abnormalities. She was treated with cyanocobalamin and folic acid. She improved and her laboratory tests got to normal gradually. Despite the name, megaloblastic anemia usually presents anemia, bicytopenia or pancytopenia and systemic manifestations. It is mandatory to search for the etiologic cause to make a complete treatment.

Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Vitamin B 12 Limits: Aged Language: Spanish Journal: Cuad. Hosp. Clín Journal subject: Medicine Year: 2022 Type: Article Affiliation country: Bolivia Institution/Affiliation country: Caja Nacional de Salud/BO

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Full text: Available Index: LILACS (Americas) Main subject: Vitamin B 12 Limits: Aged Language: Spanish Journal: Cuad. Hosp. Clín Journal subject: Medicine Year: 2022 Type: Article Affiliation country: Bolivia Institution/Affiliation country: Caja Nacional de Salud/BO