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Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
Bongomin, Felix; Kwizera, Richard; Mande, Emmanuel; Aloyo, Sharley Melissa; Achan, Beatrice; Namusobya, Martha; Sereke, Senai Goitom; Batte, Charles; Kiguli, Sarah; Baluku, Joseph Baruch; Joloba, Moses L; Kirenga, Bruce J.
  • Bongomin, Felix; Department of Medical Microbiology and Immunology, Gulu University Medical School, Gulu Uganda. Gulu. UG
  • Kwizera, Richard; Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda. Makerere. UG
  • Mande, Emmanuel; Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda. Makerere. UG
  • Aloyo, Sharley Melissa; Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda. Kampala. UG
  • Achan, Beatrice; Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda. Kampala. UG
  • Namusobya, Martha; Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda. Kampala. UG
  • Sereke, Senai Goitom; Department of Radiology and Radiotherapy, College of Health Sciences, Makerere University, Kampala, Uganda. Kampala. UG
  • Batte, Charles; Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda. Kampala. UG
  • Kiguli, Sarah; Department of Pediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda. Kampala. UG
  • Baluku, Joseph Baruch; Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda. Directorate of Programs, Mildmay Uganda, Wakiso, Uganda. Kampala. UG
  • Joloba, Moses L; Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda. Kampala. UG
  • Kirenga, Bruce J; Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda. Kampala. UG
African Health Sciences ; 22(3): 506-511, 2022-10-26. Tables
Article in English | AIM | ID: biblio-1401811
ABSTRACT
Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1-26), but follow up specimens to assess seroconversion were not available
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Full text: Available Index: AIM (Africa) Main subject: Critical Illness / Invasive Pulmonary Aspergillosis / COVID-19 Country/Region as subject: Africa Language: English Journal: African Health Sciences Year: 2022 Type: Article Institution/Affiliation country: Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda/UG / Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda/UG / Department of Medical Microbiology and Immunology, Gulu University Medical School, Gulu Uganda/UG / Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Department of Pediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Department of Radiology and Radiotherapy, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda/UG

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Full text: Available Index: AIM (Africa) Main subject: Critical Illness / Invasive Pulmonary Aspergillosis / COVID-19 Country/Region as subject: Africa Language: English Journal: African Health Sciences Year: 2022 Type: Article Institution/Affiliation country: Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda/UG / Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda/UG / Department of Medical Microbiology and Immunology, Gulu University Medical School, Gulu Uganda/UG / Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Department of Pediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Department of Radiology and Radiotherapy, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda/UG / Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda/UG