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Treatment of acquired perforant dermatoses with allopurinol / Tratamento de dermatose perfurante adquirida com alopurinol
Matsuura, Naomi Carrara; Pereira, Fernanda; Nakazato, Lissa; Copi, Luana Rocco Pereira.
  • Matsuura, Naomi Carrara; College of Medicine CERES. São José do Rio Preto. BR
  • Pereira, Fernanda; College of Medicine CERES. São José do Rio Preto. BR
  • Nakazato, Lissa; College of Medicine CERES. São José do Rio Preto. BR
  • Copi, Luana Rocco Pereira; College of Medicine CERES. São José do Rio Preto. BR
Article in English | LILACS | ID: biblio-1401946
ABSTRACT
Perforating dermatoses are papulonodular cutaneous pathologies characterized by transepithelial extrusion of components of the extracellular matrix of the dermis, by inflammation or degeneration. When secondary, the systemic diseases are called Acquired Perforating Diseases. Our letter aims to report a case of acquired perforating dermatoses secondary to chronic renal dialysis. The treatment with Allopurinol proved to be effective in this case. Allopurinol would act as an antioxidant, reducing the inflammatory reaction in tissues and consequent damage to the collagen fibers (AU)
RESUMO
Dermatoses perfurantes são patologias cutâneas papulonodulares que se caracterizam pela extrusão transepitelial de componentes da matriz extracelular da derme, por inflamação ou degeneração. Quando são secundárias as doenças sistêmicas são chamadas Doenças Perfurantes Adquiridas. Nossa carta tem como objetivo relatar caso de dermatose perfurante adquirida secundária a insuficiência renal crônica dialítica. O tratamento com Alopurinol se mostrou eficaz neste caso. O Alopurinol atuaria como antioxidante, reduzindo a reação inflamatória nos tecidos e consequentes danos nas fibras colágenas (AU)
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Full text: Available Index: LILACS (Americas) Main subject: Prurigo / Skin Diseases / Allopurinol / Perforant Pathway / Renal Insufficiency, Chronic Limits: Humans Language: English Journal: Medicina (Ribeirao Preto, Online) Journal subject: Medicina Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: College of Medicine CERES/BR

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Full text: Available Index: LILACS (Americas) Main subject: Prurigo / Skin Diseases / Allopurinol / Perforant Pathway / Renal Insufficiency, Chronic Limits: Humans Language: English Journal: Medicina (Ribeirao Preto, Online) Journal subject: Medicina Year: 2022 Type: Article Affiliation country: Brazil Institution/Affiliation country: College of Medicine CERES/BR