Effect of a ward-based outreach team and adherence game on retention and viral load suppression
South. Afr. j. HIV med. (Online)
;
23(1): 1-9, 2022. tales, figures
Article
in English
| AIM
| ID: biblio-1402438
ABSTRACT
Background:
Only 66% of South African people living with HIV (PLWH) are virologically suppressed. Therefore, it is important to develop strategies to improve outcomes.Objectives:
Assess the effect of interventions on 12-month retention in care and virological suppression in participants newly initiated on antiretroviral therapy.Method:
Fifty-seven clinics were randomised into four arms Ward-based primary health care outreach teams (WBPHCOTs); Game; WBPHCOTGame in combination; and Control (standard of care). Sixteen clinics were excluded and four re-allocated because lay counsellors and operational team leaders failed to attend the required training. Seventeen clinics were excluded due to non-enrolment.Results:
A total of 558 participants from Tshwane district were enrolled. After excluding ineligible participants, 467 participants were included in theanalysis:
WBPHCOTs (n = 72); Games (n = 126); WBPHCOTGames (n = 85); and Control (n = 184). Retention in care at 12 months was evaluable in 340 participants (86.2%) were retained in care and 13.8% were lost to follow-up. The intervention groups had higher retention in care than the Control group, but this only reached statistical significance in the Games group (96.8% vs 77.8%; relative risk [RR] 1.25; 95% confidence interval [CI] 1.131.38; P = 0.01). The 12 month virologic suppression rate was 75.3% and was similar across the four arms.Conclusion:
This study demonstrated that an adherence game intervention could help keep PLWH in care.What this study adds Evidence that interventions, especially Games, could improve retention in care
Full text:
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Index:
AIM (Africa)
Main subject:
Acquired Immunodeficiency Syndrome
/
Retention in Care
Type of study:
Controlled clinical trial
/
Etiology study
Limits:
Humans
Language:
English
Journal:
South. Afr. j. HIV med. (Online)
Year:
2022
Type:
Article
Institution/Affiliation country:
Biostatistics Unit, South African Medical Research Council/ZA
/
Department of Family Medicine, Faculty of Health Sciences, University of Pretoria/ZA
/
Department of Immunology, Faculty of Health Sciences, University of Pretoria/ZA
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