Sebaceous nevus of Jadassohn: review and clinical-surgical approach
An. bras. dermatol
;
97(5): 628-636, Sept.-Oct. 2022. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1403146
ABSTRACT
Abstract Background:
Nevus sebaceous of Jadassohn is defined as a rare congenital malformation characterized as a non-hereditary hamartoma of the adnexal structures of the skin. Its etiology is not yet well understood, but it is believed to be related to post-zygotic mutations in the HRAS, NRAS and KRAS genes.Objective:
To describe the clinical manifestation of nevus sebaceous, as well as the main management techniques addressed in the medical literature. Moreover, the present study discusses a case report of a congenital linear nevus in the left retroauricular region found in a male patient, without extracutaneous manifestations.Method:
A narrative review of the literature was carried out.Discussion:
Nevus sebaceous occurs as lesions with a linear or oval appearance, with a smooth or verrucous texture, generally alopecic and with very variable color. Moreover, nevus sebaceous is one of the components of the so-called linear nevus syndrome or Schimmelpenning-Feuerstein-Mims syndrome, which is associated with multisystemic complications. The treatment of the lesions is still controversial; however, most experts indicate surgical excision as the most frequently adopted treatment method, in addition to multidisciplinary follow-up when the diagnosis of Schimmelpenning-Feuerstein-Mims syndrome is established.Conclusion:
The linear nevus syndrome constitutes a rare manifestation; however, its diagnosis should be considered in children born with nevus sebaceous. There is no consensus yet on the best therapy, but surgical removal has shown to be a viable option.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Triângulo Mineiro/BR
Similar
MEDLINE
...
LILACS
LIS